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Role and Place of Radiation Therapy in Complex Treatment of Patients with de novo Metastatic Breast Cancer. Literature Review and Clinical Observations

https://doi.org/10.37174/2587-7593-2025-8-3-35-44

Abstract

According to state-of-art clinical guidelines, the leading method of treatment for de novo metastatic breast cancer is systemic therapy. However, the possibility and feasibility of performing local methods in treating the primary lesion in the above mentioned patients, such as surgery and radiation therapy, is currently being actively studied. This article provides a review of modern literature data related to the issues of external beam radiation therapy in patients with de novo metastatic breast cancer and presents our own clinical observations.

About the Authors

E. V. Timoshkina
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation

Ekaterina V. Timoshkina, +79104040067 

24 Kashirskoe highway, Moscow 115478 


Competing Interests:

Not declared



O. P. Trofimova
N.N. Blokhin National Medical Research Center of Oncology ; Russian Medical Academy of Continuous Professional Education
Russian Federation

24 Kashirskoe highway, Moscow 115478 

2/1 b1, Barrikadnaya str., Moscow 125993


Competing Interests:

Not declared



V. V. Glebovskaya
A.S. Loginov Moscow Clinical Scientific Center
Russian Federation

86 Enthusiasts sh., Moscow 111123


Competing Interests:

Not declared



M. V. Chernykh
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation

24 Kashirskoe highway, Moscow 115478 


Competing Interests:

Not declared



S. I. Tkachev
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation

24 Kashirskoe highway, Moscow 115478 


Competing Interests:

Not declared



S. M. Ivanov
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation

24 Kashirskoe highway, Moscow 115478 


Competing Interests:

Not declared



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Review

For citations:


Timoshkina E.V., Trofimova O.P., Glebovskaya V.V., Chernykh M.V., Tkachev S.I., Ivanov S.M. Role and Place of Radiation Therapy in Complex Treatment of Patients with de novo Metastatic Breast Cancer. Literature Review and Clinical Observations. Journal of oncology: diagnostic radiology and radiotherapy. 2025;8(3):35-44. (In Russ.) https://doi.org/10.37174/2587-7593-2025-8-3-35-44

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ISSN 2587-7593 (Print)
ISSN 2713-167X (Online)