Local Kidney Hyperplasia as an Aberrant Lobule: Complexity of CT-Differential Diagnosis with Clear-Celled Renal Tumor
https://doi.org/10.37174/2587-7593-2025-8-1-65-69
Abstract
Report of a clinical case demonstrating aberrant hyperplastic renal lobule. The mass of the lower third of the left kidney revealed in the patient at the residential prophylactic medical examination at an ultrasound. The patient was sent to oncourology hospital with suspected renal tumor for a consultation and possible treatment. The contrast-enhanced MSCT of the abdomen was performed and it revealed soft tissue mass with pronounced and uneven enhancement in the cortico-medullary and parenchymal phase, with the subsequent gradual reduction of enhancement in the excretion phase. This resulted in left kidney resection. A resection of the kidney with tumor formation is performed within safe tissues. Later, taking into the account all clinical-morphological data the removed tumor-like node in the left kidney was characterized as an abnormality in the development of the kidney in the form of an aberrant hyperplastic renal lobule. In general, it can be considered that a correct preoperative and intraoperative diagnosis in this observation was practically difficult and even impossible. That is why the definitive diagnosis was only determined by pathomorphological study of the resected macrosection. This case demonstrates the difficulty of preoperative diagnosing. This clinical case demonstrates the complexity of pre-operative diagnosis of an extremely sparse and rarely described in the world literature anomaly of the development of urogenital system — local kidney hyperplasia. The possibilities of modern diagnostic methods are limited in differential diagnosis of this anomaly with malignant kidney tumors. In this situation we were able to isolate a single indirect sign of local hyperplasia: the prolapse of the medullary layer of the kidney into the formation.
About the Authors
A. V. ArablinskiiRussian Federation
Andrei V. Arablinskii
8 build. 2, Trubetskaya str., Moscow, 119048
Competing Interests:
Not declared.
O. P. Myasnyankina
Russian Federation
Olivia P. Myasnyankina
8 build. 2, Trubetskaya str., Moscow, 119048
Competing Interests:
Not declared.
M. P. Onischenko
Russian Federation
Maksim P. Onischenko
5 build.1, 2nd Botkin proesd, Moscow, 125284
Competing Interests:
Not declared.
A. A. Sedova
Russian Federation
Anna A. Sedova
5 build.1, 2nd Botkin proesd, Moscow, 125284
Competing Interests:
Not declared.
References
1. Ivanova IE, Trefilov AA, Gusev RV. Modern views on inborn kidney abnormalities in children and early detection capabilities (literature review). Chuvashia Healthcare. 2011;1:62-70. (In Russ.)
2. Lolaeva BM, Dzheliev IS. Diagnosis of congenital kidney disease in young children. Journal of Volgograd State Medical University. 2020;3(75):56-9. (In Russ.). https://doi.org/10.19163/1994-9480-2020-3(75)-56-59.
3. Demikova NS, Lapina AS. Congenital malformations in the regions of the Russian Federation: results of monitoring in 2000-2010. Russian Bulletin of Perinatology and Pediatrics. 2012;57(2):91-8. (In Russ.).
4. Olhova EB. Anomalies of kidneys development at children. Ultrasound diagnostics. Medical Visualization. 2011;6:136-7. (In Russ.).
5. Ayvazyan AV, Voyno-Yasenetsky MA. Malformations of the kidney and ureters. Moscow, 2008. 18 p. (In Russ.).
6. Karanadze EN. Ultrasound diagnostics of congenital disease of development of the urinary system in the fetus and newborn children: study guide. Krasnodar: Kuban State Medical University, 2016. 26 p. (In Russ.).
7. Bykovskiy VA. Echography of abdominal pathology in children. Moscow, 2001. 184 p. (In Russ.).
8. Buylov VM. Difficulties and mistakes of ultrasound and X-ray diagnostics of pseudo-tumours of kidneys. SonoAce-Ultrasound. 2003;11:3-9. (In Russ.).
9. Galchina YuS, Glotov AV, Pyanikin SS. Contrast-Enhanced MDCT in Clear Cell Renal Adenocarcinoma: Correlation with Fuhrman Grade. Medical Visualization. 2016;3:35-49. (In Russ.).
10. Solovyev YaA, Mitina LA, Alekseev BYa. Use of the contrast agent in the ultrasound diagnosis of kidney tumors. P.A. Herzen Journal of Oncology. 2017;6(5):37-43. (In Russ.). https://doi.org/10.17116/onkolog20176537-43.
Review
For citations:
Arablinskii A.V., Myasnyankina O.P., Onischenko M.P., Sedova A.A. Local Kidney Hyperplasia as an Aberrant Lobule: Complexity of CT-Differential Diagnosis with Clear-Celled Renal Tumor. Journal of oncology: diagnostic radiology and radiotherapy. 2025;8(1):65-69. (In Russ.) https://doi.org/10.37174/2587-7593-2025-8-1-65-69