PET/CT with 68Ga-FAPI and 18F-FDG in the Detection of Metastases in Regional Lymph Nodes in Gastric Cancer
https://doi.org/10.37174/2587-7593-2025-8-1-29-35
Abstract
Purpose: To determine the diagnostic effectiveness of PET/CT with 68Ga-FAPI in gastric cancer.
Matreial and Methods:The study included 42 patients with histologically confirmed gastric cancer. All patients underwent PET/CT with 68Ga-FAPI and PET/CT with 18F-FDG. The diagnostic accuracy of the methods was compared based on sensitivity and specificity parameters in detecting metastatic involvement of regional lymph nodes. Data assessment was conducted based on histologically verified disease and clinical follow-up data.
Results: PET/CT with 68Ga-FAPI is a more effective diagnostic method for detecting metastases in regional lymph nodes compared to PET/CT with 18F-FDG. Our results support the clinical potential of PET/CT with 68Ga-FAPI for improved diagnosis and treatment planning in gastric cancer.
About the Authors
E. V. Belkin
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation
Competing Interests:
Russian Federation
Egor V. Belkin
24 Kashirskoye Shosse, Moscow, 115478
Competing Interests:
Not declared
P. E. Tulin
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation
Competing Interests:
Russian Federation
Pavel E. Tulin
24 Kashirskoye Shosse, Moscow, 115478
Competing Interests:
Not declared
O. B. Abu-Khaydar
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation
Competing Interests:
Russian Federation
Omar B. Abu-Khaydar
24 Kashirskoye Shosse, Moscow, 115478
Competing Interests:
Not declared
I. A. Skripachev
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation
Competing Interests:
Russian Federation
Ivan A. Skripachev
24 Kashirskoye Shosse, Moscow, 115478
Competing Interests:
Not declared
A. V. Filimonov
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation
Competing Interests:
Russian Federation
Alexander V. Filimonov
24 Kashirskoye Shosse, Moscow, 115478
Competing Interests:
Not declared
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Review
For citations:
Belkin E.V., Tulin P.E., Abu-Khaydar O.B., Skripachev I.A., Filimonov A.V. PET/CT with 68Ga-FAPI and 18F-FDG in the Detection of Metastases in Regional Lymph Nodes in Gastric Cancer. Journal of oncology: diagnostic radiology and radiotherapy. 2025;8(1):29-35. (In Russ.) https://doi.org/10.37174/2587-7593-2025-8-1-29-35
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