Gadoxetic Acid-Enhanced MRI for the Detection of Hepatocellular Carcinoma
https://doi.org/10.37174/2587-7593-2018-1-1-37-39
Abstract
To specify the possibilities for application of the liver-specific contrast agent (gadoxetic acid) in MRI with diffusion-weighted images (DWI) in the diagnosis of hepatocellular carcinoma (HCC).
Results: On the basis of the data obtained, we identified a complex of semiotic features that allow the tumor to be correctly differentiated as a HCC, namely:
- hypointensity on T1-weighted images (р > 0.1)
- hyperintensity on DWI (р < 0.001)
- diffuse heterogeneous enhancement in the early phases (р < 0.001)
- hypointensity in the hepatobiliary phase (р = 0.013)
Conclusions: The complex of revealed semiotic features based on the combination of the liver-specific contrast agent (gadoxetic acid) in MRI with DWI makes it possible to reliably recognize the HCC among other neoplasms of the liver (sensitivity 100 %, specificity 91.7 %, accuracy 97.1 %).
About the Authors
B. N. Medvedeva
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation
Russian Federation
A. B. Lukyanchenko
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation
Russian Federation
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Review
For citations:
Medvedeva B.N., Lukyanchenko A.B. Gadoxetic Acid-Enhanced MRI for the Detection of Hepatocellular Carcinoma. Journal of oncology: diagnostic radiology and radiotherapy. 2018;1(1):37-39. (In Russ.) https://doi.org/10.37174/2587-7593-2018-1-1-37-39
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