Preview

Journal of oncology: diagnostic radiology and radiotherapy

Advanced search

Punctural Percutaneous Image-Guided Cryoablation for Pain Relief in Bone Metastases

https://doi.org/10.37174/2587-7593-2022-5-1-65-73

Abstract

Percutaneous image-guided cryoablation (PICA) in relieve pain from metastatic bone disease was performed in 24 patients. The cryoprobes were navigated and the ice sphere was monitored using computed tomography. Each patient, depending on the volume of the lesion, underwent from one to four ablations. Pain assessment was performed using a numerical rank scale. A decrease in the pain index after PICA was from 4.1±0.8 points to 1.3±0.5 points. The duration of analgesic affect correlated with local control of the tumor. A later postoperative complication was noted in one case in the form of a bone fracture in the ablation zone. Further study of the effectiveness of this technology is necessary by analyzing larger samples and comparing them with the results of treatment with other methods of local exposure.

About the Authors

I. A. Burovik
N.N. Petrov National Medical Research Center of Oncology; Saint-Petersburg UniversitySaint-Petersburg University
Russian Federation

68, Leningradskaya street, Pesochny, St. Petersburg, 197758

7/9, Universitetskaya emb, St. Petersburg, 199034



G. G. Prokhorov
N.N. Petrov National Medical Research Center of Oncology
Russian Federation

68, Leningradskaya street, Pesochny, St. Petersburg, 197758



S. S. Bagnenko
N.N. Petrov National Medical Research Center of Oncology; St. Petersburg State Pediatric Medical University
Russian Federation

68, Leningradskaya street, Pesochny, St. Petersburg, 197758

2, Litovskaya street, St. Petersburg, 194100



L. N. Shevkunov
N.N. Petrov National Medical Research Center of Oncology
Russian Federation

68, Leningradskaya street, Pesochny, St. Petersburg, 197758



A. A. Meldo
Saint-Petersburg clinical and practical center of specialized types of medical care (oncological)
Russian Federation

Litera A, 68a, Leningradskaya Str., Pesochny, St. Petersburg, 197758



R. R. Gilfanova
N.N. Petrov National Medical Research Center of Oncology
Russian Federation

68, Leningradskaya street, Pesochny, St. Petersburg, 197758



D. Yu. Levin
N.N. Petrov National Medical Research Center of Oncology
Russian Federation

68, Leningradskaya street, Pesochny, St. Petersburg, 197758



References

1. Macedo F, Ladeira K, Pinho F, et al. Bone metastases: an overview. Oncol Reviews. 2017;11(1):43-9. DOI: 10.4081/oncol.2017.321, PMID: 28584570.

2. Cheung FH. The Practicing orthopedic surgeon’s guide to managing long bone metastases. Orthopedic Clinics of North America. 2014;45(1)109-+, DOI: 10.1016/j.ocl.2013.09.003, PMID: 24267212.

3. Weber KL, Randall RL, Grossman S, Parvizi J. Management of lower-extremity bone metastasis. J Bone Joint Surgery — Am Volume. 2006;88A:11-9. DOI: 10.2106/JBJS.F.00635, PMID: 17142431.

4. Jehn CF, Diel IJ, Overkamp F, et al. Management of metastatic bone disease algorithms for diagnostics and treatment. Anticancer Res. 2016;36(6):2631-37, PMID: 27272771.

5. Kurup AN, Morris JM, Callstrom MR, Ablation of musculoskeletal metastases. Am J Roentgenol. 2017;209(4):713-21. DOI: 10.2214/AJR.17.18527, PMID: 28777648.

6. Zeng L, Chow E, Bedard G et al. Quality of life after palliative radiation therapy for patients with painful bone metastases: results of an international study validating the EORTC QLQ-BM22. Int J Radiat Oncol Biol Phys. 2012;84(3):E337-42. DOI: 10.1016/j.ijrobp.2012.05.028, PMID: 22763028.

7. Munk PL, Rashid F, Heran MK, et al. Combined cementoplasty and radiofrequency ablation in the treatment of painful neoplastic lesions of bone. J Vasc Intervent Radiol. 2009;20(7):903-11. DOI: 10.1016/j.jvir.2009.03.035, PMID: 19481469.

8. Callstrom MR, Atwell TD, Charboneau JW, et al. Painful metastases involving bone: Percutaneous image-guided cryoablation — Prospective trial interim analysis. Radiology. 2006;241(2):572-80. DOI: 10.1148/radiol.2412051247, PMID: 17057075.

9. Belyaev AM, Prokhorov GG, Burovik IA, Okonechnikova DV, Сryoablation technology for bone metastases. Problems in Oncol. 2021;67(4)554-8. (In Russian) DOI: 10.37469/0507-3758-2021-67-4-554-558.

10. Coleman R, Body JJ, Aapro M, et al. Bone health in cancer patients: ESMO Clinical Practice Guidelines. Ann Oncol. 2014;25:124-37. DOI: 10.1093/annonc/mdu103, PMID: 24782453.

11. Ripamonti CI, Santini D, Maranzano E, et al. Management of cancer pain: ESMO Clinical Practice Guidelines. Ann Oncol. 2012;23:139-54, DOI:10.1093/annonc/mds233, PMID: 22997447.

12. Vardy J, Agar M. Nonopioid drugs in the treatment of cancer pain. J Clin Oncol. 2014;32(16):1677-90. DOI: 10.1200/JCO.2013.52.8356, PMID: 24799483.

13. Al Husaini H, Wheatley-Price P, Clemons M, Shepherd FA, Prevention and management of bone metastases in lung cancer: a review. J Thor Oncol. 2009;4(2):251-9. DOI: 10.1097/JTO.0b013e31819518fc, PMID: 19179905.

14. Hussain A, Aly A, Mullins CD, et al. Risk of skeletal related events among elderly prostate cancer patients by site of metastasis at diagnosis. Cancer Med. 2016;5(11):3300-9. DOI: 10.1002/cam4.914, PMID: 27730756.

15. Santini D, Barni S, Intagliata S, Falcone A. Natural history of non-small-cell lung cancer with bone metastases. Sci Rep. 2015;5. DOI: 10.1038/srep18670, PMID: 26690845

16. Yong M, Jensen AO, Jacobsen JB, et al. Survival in breast cancer patients with bone metastases and skeletal-related events: a population-based cohort study in Denmark (1999–2007). Breast Cancer Res Treat. 2011;129(2):495-503. DOI: 10.1007/s10549-011-1475-5, PMID: 21461730.

17. Chi MS, Yang KL, Chang YC, et al. Comparing the effectiveness of combined external beam radiation and hyperthermia versus external beam radiation alone in treating patients with painful bony metastases: a phase 3 prospective, randomized, controlled trial. Int J Radiat Oncol Biol Phys. 2018;100(1):78-87. DOI: 10.1016/j.ijrobp.2017.09.030, PMID: 29066122.

18. Choi J, Raghavan M. Diagnostic imaging and image-guided therapy of skeletal metastases. Cancer Control. 2012;19(2):102-12. DOI: 10.1177/107327481201900204, PMID: 22487972.

19. Dennis K, Makhani L, Zeng L, et al. Single fraction conventional external beam radiation therapy for bone metastases: A systematic review of randomised controlled trials. Radiother Oncol. 2013;106(1):5-14. DOI: 10.1016/j.radonc.2012.12.009, PMID: 23321492.

20. Lutz S, Berk L, Chang E, et al. Palliative radiotherapy for bone metastases: an astro evidence-based guideline. Int J Radiat Oncol Biol Phys.2011;79(4):965-76. DOI: 10.1016/j.ijrobp.2010.11.026, PMID: 21277118.

21. Laufer I, Rubin DG, Lis E, et al. The NOMS Framework: approach to the treatment of spinal metastatic tumors. Oncologist. 2013;18(6):744-51. DOI: 10.1634/theoncologist.2012-0293, PMID: 23709750.

22. Piccioli A, Spinelli MS, Maccauro G. Impending fracture: A difficult diagnosis. Injury-Int J Care Injured. 2014;45:S.138-141. DOI: 10.1016/j.injury.2014.10.038, PMID: 25457334.

23. Dupuy DE, Liu DW, Hartfeil D, et al. Percutaneous radiofrequency ablation of painful osseous metastases: a multicenter American College of Radiology imaging network trial. Cancer. 2010 Feb;116(4):989-97. DOI: 10.1002/cncr.24837, PMID: 20041484.

24. Burovik IA, Prokhorov GG. Computed tomography as a method of control of percutaneous tumor cryoablation. Diagnostic Radiology and Radiotherapy. 2019;(4):57-65. (In Russian.) DOI: 10.22328/2079-5343-2019-10-4-57-65.

25. Hurwitz MD, Ghanouni P, Kanaev SV, et al. Magnetic resonance-guided focused ultrasound for patients with painful bone metastases: phase II trial results. J Nat Cancer Inst. 2014;106(5). DOI: 10.1093/jnci/dju082, PMID: 24760791.

26. Ballantyne JC, Mao JR. Opioid therapy for chronic pain. New England J Med. 2003;349(20):1943-53. DOI: 10.1056/NEJMra025411, PMID: 14614170.

27. Carlson CL. Effectiveness of the World Health Organization cancer pain relief guidelines: an integrative review. J Pain Res. 2016;9:515-534. DOI: 10.2147/JPR.S97759, PMID: 27524918.


Review

For citations:


Burovik I.A., Prokhorov G.G., Bagnenko S.S., Shevkunov L.N., Meldo A.A., Gilfanova R.R., Levin D.Yu. Punctural Percutaneous Image-Guided Cryoablation for Pain Relief in Bone Metastases. Journal of oncology: diagnostic radiology and radiotherapy. 2022;5(1):65–73. (In Russ.) https://doi.org/10.37174/2587-7593-2022-5-1-65-73

Views: 389


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2587-7593 (Print)
ISSN 2713-167X (Online)