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Difficulties of Differential Diagnosis of Hurthle Cell Thyroid Tumor

https://doi.org/10.37174/2587-7593-2021-4-3-94-100

Abstract

Purpose: Assessment of the capabilities of the ultrasound method in the diagnostics of a rare Hurthle-cell tumor of the thyroid gland on the example of a clinical case of a patient with malignant neoplasms of independent primary multiple localizations in comparison with other research methods.

Material and methods: A comprehensive study of materials from the history of the disease, the results of clinical, laboratory, instrumental, morphological research methods and their comparison with diagnostic cases from literature data.

Results: Despite the full comprehensive examination of the patient, including ultrasound, MRI, PET/CT, puncture biopsy under ultrasound control, it was not possible to make the correct diagnosis before the operation. The presence of other malignant diseases in the patient’s history, the presence of altered paratracheal nodes in the same zone, and the rare occurrence of Hurthle thyroid tumors played a role.

Conclusions: Hurthle-thyroid cell tumors are a rare disease, but it must always be taken into account in the diagnostic search, since even benign Hurthle tumors have a high risk of malignancy and spreading of distant metastases. 

About the Authors

T. Yu. Danzanova
N.N. Blokhin National Medical Research Center of Oncology; N.I. Pirogov Russian National Research Medical University
Russian Federation

24 Kashirskoye Highway, Moscow, 115478;

1 Ostrovityanov St., Moscow, 117997



E. A. Gudilina
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation

24 Kashirskoye Highway, Moscow, 115478



A. A. Kalinina
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation

24 Kashirskoye Highway, Moscow, 115478



P. I. Lepedatu
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation

24 Kashirskoye Highway, Moscow, 115478



G. T. Sinyukova
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation

24 Kashirskoye Highway, Moscow, 115478



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Review

For citations:


Danzanova T.Yu., Gudilina E.A., Kalinina A.A., Lepedatu P.I., Sinyukova G.T. Difficulties of Differential Diagnosis of Hurthle Cell Thyroid Tumor. Journal of oncology: diagnostic radiology and radiotherapy. 2021;4(3):94-100. (In Russ.) https://doi.org/10.37174/2587-7593-2021-4-3-94-100

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ISSN 2587-7593 (Print)
ISSN 2713-167X (Online)