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Magnetic Susceptibility MRI in Differential Diagnostics of Primary CNS Lymphoma and Anaplastic Astrocytoma Clinical Observation

https://doi.org/10.37174/2587-7593-2020-3-4-94-100

Abstract

Primary lymphomas of the central nervous system (PCLCS) are relatively rare tumors, usually having a multifocal manifestation in the brain and rapid progression. It is not always possible to make a correct diagnosis for MRI, since similar radiological manifestations (markers) of this disease, when using routine protocols, MRI can occur, for example, in malignant gliomas. This article presents a clinical case of a refinement diagnosis — PLCNS when using MRI in sequence (SWI), which was confirmed by the data of histological examination of surgical material.

About the Authors

D. V. Sashin
N.N. Blokhin National Medical Research Center of Oncology»
Russian Federation
24 Kashirskoye Highway, Moscow, 115478


M. B. Dolgushin
N.N. Blokhin National Medical Research Center of Oncology»
24 Kashirskoye Highway, Moscow, 115478


E. A. Kobyakova
N.N. Blokhin National Medical Research Center of Oncology»
24 Kashirskoye Highway, Moscow, 115478


E. A. Nechipay
N.N. Blokhin National Medical Research Center of Oncology»
24 Kashirskoye Highway, Moscow, 115478


T. G. Gasparyan
N.N. Blokhin National Medical Research Center of Oncology»
24 Kashirskoye Highway, Moscow, 115478


References

1. Bublievskii DV, Evzikov GYu. Neurosurgery. 2012;12(1):74‑81. (In Russ.). DOI: 10.17650/1683‑3295‑2012‑12‑1‑74‑81.

2. Voloshin SV, Krivolapov YuA, Gubarina NS, Shmidt AV, Fominyh MS, Potihinova NA, et al. Primary B‑cell lymphoma of the central nervous system (PCLCS): modern concepts about pathogenesis, diagnostic and treatment. Messenger of Hematology. 2011;3:22‑34. (In Russ.).

3. Ding Y, Xing Z, Liu B, Lin X, Cao D. Differentiation of primary central nervous system lymphoma from high-grade glioma and brain metastases using susceptibility-weighted imaging. Brain Behav. 2014;4(6):841‑9. DOI: 10.1002/brb3.288.

4. Nechipay EA, Dolgushin MB, Pronin IN, Bekyashev AK, Kobyakova EA, Fadeeva LM, et al. DCE MRI in Differential Diagnosis of Primary and Secondary Brain Tumors. Medical Visualization. 2015;(4):18‑ 30. (In Russ.).

5. Hayat MA. Tumor of Central Nervous System. Netherlands: Springer, 2011. Vol. 1. 434 p.

6. Akberov RF, Yaminov IH, Safiullin RR, Puzakin EV. Diagnostics of brain tumors: capabilities of magnetic resonance tomography. Practic Medicine. 2011;1(49):54‑7. (In Russ.).

7. Bagley LJ, Grossman RI, Judy KD, Curtis M, Loevner LA, Polansky M, et al. Gliomas: correlation of magnetic susceptibility artifact with histologic grade. Radiology. 1997;202(2):511‑6. DOI: 10.1148/ radiology.202.2.9015082.

8. Park MJ, Kim HS, Jahng GH, Ryu CW, Park SM, Kim SY. Semiquantitative assessment of intratumoral susceptibility signals using non‑contrast‑enhanced high-field high‑resolution susceptibility‑weighted imaging in patients with gliomas: comparison with MR perfusion imaging. AJNR Am J Neuroradiol. 2009;30(7):1402‑8. DOI: 10.3174/ajnr.A1593.

9. Radbruch A, Wiestler B, Kramp L, Lutz K, Bäumer Ph, Weiler M, et al. Differentiation of glioblastoma and primary CNS lymphomas using susceptibility weighted imaging. Eur J Radiol. 2013;82(3):552‑6. DOI: 10.1016/j.ejrad.2012.11.002.

10. Kickingereder P, Wiestler B, Sahm F, Heiland S, Roethke M, Schlemmer HP, et al. Primary central nervous system lymphoma and atypical glioblastoma: multiparametric differentiation by using diffusion‑, perfusion‑, and susceptibility‑weighted MR imaging. Radiology. 2014;272(3):843‑50. DOI: 10.1148/radiol.14132740.

11. Yangzong Wu, Zhihong Den, Yuanxiang Lin, Accuracy of susceptibility weighted imaging and dynamic susceptibility contrast MRI for differentiating high — grade glioma from primary CNS lymphomas: a meta — analysis. World Neurosurgery. 2018;18:141‑4. DOI:10.1016/j.wneu.2018.01.098.

12. Kim HS, Jahng GH, Ryu CW, Kim SY. Added value and diagnostic performance of intratumoral sus-ceptibility signals in the differential diagnosis of solitary enhancing brain lesions: preliminary study. AJNR Am J Neuroradiol. 2009;30(8):1574‑9. DOI: 10.3174/ajnr.A1635.

13. Radbruch A, Wiestler B, Kramp L, Lutz K, Bäumer Ph, Weiler M, et al. Differentiation of glioblastoma and primary CNS lymphomas using susceptibility weighted imaging. Eur J Radiol. 2013;82(3):552‑6. DOI: 10.1016/j.ejrad.2012.11.002

14. Aydin O, Buyukkaya R, Hakyemez B. Susceptibility Imaging in Glial Tumor Grading; Using 3 Tesla Magnetic Resonance (MR) System and 32 Channel Head Coil. Pol J Radiol. 2017;82:179‑87. Published 2017 Apr 1. DOI: 10.12659/PJR.900374.

15. Peters S, Knöß N, Wodarg F, Cnyrim C, Jansen O. Glioblastomas vs. lymphomas: more diagnostic certainty by using susceptibility‑weighted imaging (SWI). Rofo. 2012;184(8):713‑8. DOI: 10.1055/s‑0032‑1312862

16. Kickingereder P, Wiestler B, Sahm F, Heiland S, Roethke M, Schlemmer HP, et al. Primary central nervous system lymphoma and atypical glioblastoma: multiparametric differentiation by using diffusion‑, perfusion‑, and susceptibility‑weighted MR imaging. Radiology. 2014;272(3):843‑50. DOI: 10.1148/radiol.14132740.


Review

For citations:


Sashin D.V., Dolgushin M.B., Kobyakova E.A., Nechipay E.A., Gasparyan T.G. Magnetic Susceptibility MRI in Differential Diagnostics of Primary CNS Lymphoma and Anaplastic Astrocytoma Clinical Observation. Journal of oncology: diagnostic radiology and radiotherapy. 2020;3(4):94-100. (In Russ.) https://doi.org/10.37174/2587-7593-2020-3-4-94-100

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ISSN 2587-7593 (Print)
ISSN 2713-167X (Online)