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Difficulties of Differential Diagnostics of Idiopathic Granulomatous Mastitis with Contrast Enhanced Visualization Methods

https://doi.org/10.37174/2587-7593-2020-3-3-83-92

Abstract

Mastitis is an inflammatory condition of the breast, which may or may not be accompanied by infection (WHO 2000).
Idiopathic granulomatous mastitis is one of the forms of non-infectious mastitis. Granulomatous lobular mastitis is a rare inflammatory disease of the breast that was first described by Kessler and Wolloch in 1972.
Idiopathic granulomatous mastitis (IGM) or granulomatous lobular mastitis is chronic inflammatory breast disease of unknown etiology, the clinical manifestation and radiological features of which may mimic other nosological entities.
We report a case of 29 year old woman who was diagnosed with breast carcinoma by radiological methods, such as contrast enhanced spectral mammography (CESM), magnetic resonance imaging with dynamic contrast enhancement (MRI with DCE), SPECT/CT. However, performed core needle biopsy of a lesion shows no tumor cells. The conservative treatment was suggested, based on obtained information.
Aim is a review of radiological features of IGM with contrast enhanced visualization methods, based on our clinical case; description of differential radiological features in comparison with similar diseases of the breast, such as inflammatory breast carcinoma, tuberculosis etc.

About the Authors

A. V. Chernaya
N.N. Petrov National Medical Research Centre of Oncology
Russian Federation
68, Leningradskaya street, Pesochny, St. Petersburg, 1977581.
Competing Interests: Not declared.


A. V. Reva
V.A. Almazov National Medical Research Centre
Russian Federation
2 Akkuratova street, St. Petersburg, 197341.
Competing Interests: Not declared.


R. Kh. Ulianova
N.N. Petrov National Medical Research Centre of Oncology
Russian Federation
68, Leningradskaya street, Pesochny, St. Petersburg, 1977581.
Competing Interests: Not declared.


L. N. Shevkunov
N.N. Petrov National Medical Research Centre of Oncology
Russian Federation
68, Leningradskaya street, Pesochny, St. Petersburg, 1977581.
Competing Interests: Not declared.


P. V. Krivorotko
N.N. Petrov National Medical Research Centre of Oncology
Russian Federation
68, Leningradskaya street, Pesochny, St. Petersburg, 1977581.
Competing Interests: Not declared.


S. A. Tyatkov
N.N. Petrov National Medical Research Centre of Oncology
Russian Federation
68, Leningradskaya street, Pesochny, St. Petersburg, 1977581.
Competing Interests: Not declared.


S. A. Gharibyan
N.N. Petrov National Medical Research Centre of Oncology
Russian Federation
68, Leningradskaya street, Pesochny, St. Petersburg, 1977581.
Competing Interests: Not declared.


V. V. Danilov
N.N. Petrov National Medical Research Centre of Oncology
Russian Federation
68, Leningradskaya street, Pesochny, St. Petersburg, 1977581.
Competing Interests: Not declared.


A. S. Petrova
N.N. Petrov National Medical Research Centre of Oncology
Russian Federation
68, Leningradskaya street, Pesochny, St. Petersburg, 1977581.
Competing Interests: Not declared.


E. K. Zhiltsova
N.N. Petrov National Medical Research Centre of Oncology
Russian Federation
68, Leningradskaya street, Pesochny, St. Petersburg, 1977581.
Competing Interests: Not declared.


P. I. Krzhivitskii
N.N. Petrov National Medical Research Centre of Oncology
Russian Federation
68, Leningradskaya street, Pesochny, St. Petersburg, 1977581.
Competing Interests: Not declared.


V. O. Smirnova
N.N. Petrov National Medical Research Centre of Oncology
Russian Federation
68, Leningradskaya street, Pesochny, St. Petersburg, 1977581.
Competing Interests: Not declared.


A. N. Zaitsev
N.N. Petrov National Medical Research Centre of Oncology
Russian Federation
68, Leningradskaya street, Pesochny, St. Petersburg, 1977581.
Competing Interests: Not declared.


References

1. Goulabchand R, Hafidi A, Van de Perre P, et al. Mastitis in Autoimmune Diseases: Review of the Literature, Diagnostic Pathway and Pathophysiological Key Players. J Clin Med. 2020;9:958. DOI:10.3390/jcm9040958.

2. Altintoprak F, Karakece E, Kivilcim T, et al. Idiopathic granulomatous mastitis: an autoimmune disease? Sci World J. 2013:(4):148727. DOI: 10.1155/2013/148727. eCollection 2013.

3. Chinyama CN, Idiopathic Granulomatous Mastitis. Benign Breast Diseases. 2014:76-84. DOI 10.1007/978-3-642-41065-9.

4. Nikolaev A, Blake CN, Carlson DL. Association between hyperprolactinemia and granulomatous mastitis. Breast J. 2016;22(2):224-31.

5. Kok KY, Telisinghe PU. Granulomatous mastitis: presentation, treatment and outcome in 43 patients. Surgeon. 2010;8(4):197-201.

6. Taylor GB, Paviour SD, Musaad S, et al. A clinico-pathological review of 34 cases of inflammatory breast disease showing an association between corynebacteria infection and granulomatous mastitis. Pathology. 2003;35(2):109-19.

7. Gautier N, Lalonde L, Tran-Thanh D, et al. Chronic granulomatous mastitis: imaging, pathology and management. Eur J Radiol. 2013;82(4):e165-e175.

8. Baslaim MM, Khayat HA, Al-Amoudi SA. Idiopathic granulomatous mastitis: a heterogeneous disease with variable clinical presentation. World J Surg. 2007;31(8):1677-81.

9. Aghajanzadeh M, Hassanzadeh R, Alizadeh Sefat S, et al. Granulomatous mastitis: presentations, diagnosis, treatment and outcome in 206 patients from the North of Iran. Breast. 2015;24(4):456-60.

10. Gautier N, Lalonde L, Tran-Thanh D, et al. Chronic granulomatous mastitis: imaging, pathology and management. Eur J Radiol. 2013;82(4):e165-e175.

11. Fazzio RT, Shah SS, Sandhu NP. Idiopathic granulomatous mastitis: imaging update and review. Insights Imaging. 2016;7(4):531-9.

12. Oztekin PS, Durhan G, Nercis Kosar P, et al. Imaging findings in patients with granulomatous mastitis. Iran J Radiol. 2016;13(3):e33900.

13. Yukawa M, Watatani M, Isono S, et al. Management of granulomatous mastitis: a series of 13 patients who were evaluated for treatment without corticosteroids. Int Surg. 2015;100(5):774-82.

14. Gautier N, Lalonde L, Tran-Thanh D, et al. Chronic granulomatous mastitis: imaging, pathology and management. Eur J Radiol. 2013;82(4): e165-e175.

15. Bassler R, Histopathologie, Giess CS, et al. Clinical experience with aspiration of breast abscesses based on size and etiology at an academic medical center. J Clin Ultrasound. 2014;42(9):513-21.

16. Martinez-Ramos D, Simon-Monterde L, Suelves-Piqueres C, et al. Idiopathic granulomatous mastitis: A systematic review of 3060 patients. Breast J. 2019;00:1-6. DOI: 10.1111/tbj.13446.

17. Seo HR, Na KY, Yim HE, et al. Differential diagnosis in idiopathic granulomatous mastitis and tuberculous mastitis. J Breast Cancer. 2012;15(1):111-8.

18. Pluguez-Turull CW, Nanyes J E, et al. Idiopathic Granulomatous Mastitis: Manifestations at Multimodality Imaging and Pitfalls. RadioGraphics. 2018;38:330-56.

19. Dilaveri CA, Mac Bride MB, Sandhu NP, et al. Breast manifestations of systemic diseases. Int J Womens Health. 2012;4:35-43.

20. Poyraz N, Emlik GD, Batur A, et al. Magnetic resonance imaging features of idiopathic granulomatous mastitis: a retrospective analysis. Iran J Radiol. 2016;13(3):e20873.

21. Dursun M, Yilmaz S, Yahyayev A, et al. Multimodality imaging features of idiopathic granulomatous mastitis: outcome of 12 years of experience. Radiol Med (Torino). 2012;117(4):529-38.

22. Dawood S, Cristofanilli M. Inflammatory breast cancer: what progress have we made? Oncology (Williston Park). 2011;25(3):264-70, 273.

23. Dershaw DD, Moore MP, Liberman L, et al. Inflammatory breast carcinoma: mammographic findings. Radiology. 1994;190(3):831-4.

24. Kamal RM, Hamed ST, Salem DS. Classification of inflammatory breast disorders and step by step diagnosis. Breast J. 2009;15(4):367-80.

25. Yildiz S, Aralasmak A, Kadioglu H, et al. Radiologic findings of idiopathic granulomatous mastitis. Med Ultrason. 2015;17(1):39-44.

26. Hovanessian Larsen LJ, Peyvandi B, Klipfel N, et al. Granulomatous lobular mastitis: imaging, diagnosis, and treatment. AJR Am J Roentgenol. 2009;193(2):574-81.

27. Yilmaz E, Lebe B, Usal C, et al. Mammographic and sonographic findings in the diagnosis of idiopathic granulomatous mastitis. Eur Radiol. 2001;11(11):2236-40.

28. Ozturk M, Mavili E, Kahriman G, et al. Granulomatous mastitis: radiological findings. Acta Radiol. 2007;48(2):150-5.

29. An JK, Woo JJ, Lee SA. Non-puerperal mastitis masking pre-existing breast malignancy: importance of follow-up imaging. Ultrasonography. 2016;35(2):159-63.


Review

For citations:


Chernaya A.V., Reva A.V., Ulianova R.Kh., Shevkunov L.N., Krivorotko P.V., Tyatkov S.A., Gharibyan S.A., Danilov V.V., Petrova A.S., Zhiltsova E.K., Krzhivitskii P.I., Smirnova V.O., Zaitsev A.N. Difficulties of Differential Diagnostics of Idiopathic Granulomatous Mastitis with Contrast Enhanced Visualization Methods. Journal of oncology: diagnostic radiology and radiotherapy. 2020;3(3):83-92. (In Russ.) https://doi.org/10.37174/2587-7593-2020-3-3-83-92

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ISSN 2587-7593 (Print)
ISSN 2713-167X (Online)