Preview

Journal of oncology: diagnostic radiology and radiotherapy

Advanced search

The Capabilities of the Combi-Elasto and CEUS Ultrasound modes in the Diagnosis of Viral Hepatitis B

https://doi.org/10.37174/2587-7593-2020-3-3-75-82

Abstract

Purpose: To evaluate the capabilities of the Combi-Elasto and CEUS ultrasound modes in the diagnosis of viral hepatitis B on the clinical case example of the middle-aged patient with chronic viral hepatitis B in the acute stage.
Material and methods: Comprehensive study of the patient's medical history, outpatient medical record, results of clinical, laboratory, instrumental and morphological methods with independent retrospective analysis of the histologic specimen of the liver.
Results: The materials of observation and diagnostic search of the 54-year-old patient with chronic viral hepatitis B in the acute stage are presented. The diagnosis establishing took 3 months of examination in the infectious department and morphological study. This episode of the disease debuted with abdominal discomfort, weakness, yellowing of the sclera and skin, darkening of the urine and lightening of the feces. Survey the following results were obtained: Combi-Elasto data on admission — fibrosis F4 of the METAVIR scale (2.09), expressed process activity (1.60), absence of steatosis (0.54). At the initial stage, CEUS was performed with an assessment of quantitative and qualitative parameters on the same equipment, cirrhosis of the liver was excluded, chronic viral hepatitis, the acute stage was diagnosed, and appropriate treatment was prescribed. As a result of systematic observation after 3 months of repeated Combi-Elasto, the following results were obtained: fibrosis F1-2 of the METAVIR scale (1,30), average process activity (1.26), absence of steatosis (0.55).
Conclusion: The presented clinical observation demonstrates the high efficiency of combining 2 modes (Combi-Elasto and CEUS) on the same equipment in the diagnosis of chronic viral hepatitis in the acute stage.

 

About the Authors

A. V. Tikhankova
Scientific-Research Laboratory «Diagnostic Study and Miniinvasive Technologies» of Smolensk State Medical University
Russian Federation
28, Krupskoy st., Smolensk, 214019.
Competing Interests:

Not declared.



A. V. Borsukov
Scientific-Research Laboratory «Diagnostic Study and Miniinvasive Technologies» of Smolensk State Medical University
Russian Federation
28, Krupskoy st., Smolensk, 214019.
Competing Interests:

Not declared.



A. O. Buyeverov
I.M. Sechenov First Moscow State Medical University
Russian Federation
8, build. 2, Trubetskaya st., Moscow, 119991.
Competing Interests:

Not declared.



T. S. Bezmenova
Smolensk State Medical University
Russian Federation
28, Krupskoy st., Smolensk, 214019.
Competing Interests:

Not declared.



K. A. Gladarevskij
Clinical Hospital №1
Russian Federation
40, Frunze st., Smolensk, 214006.
Competing Interests:

Not declared.



References

1. Kuntz E, Kuntz H-D. Hepatology: principles and practice. 2nd ed. Springer Medizin Verlag Heidelberg, 2006. 902 p.

2. Schiff UR. Viral hepatitis and cholestatic diseases. Edited by Sorrell MF, Maddray US. Translated from Engl. Ed. Ivashkin VT et al. Series «Liver Diseases by Schiff». M. GEOTAR-Media/ 2010. 408 p. (In Russ.).

3. Buyeverov AO. Elastography — a new method for noninvasive diagnosis of liver fibrosis. Hepatological Forum. 2007;(2):14-8. (In Russ.).

4. Kamalov YuR, Khutornoy IV, Kryzhanovskaya I, Filin AV, Morozova MM. Point shear wave elastography (ARFI-elastometry) in chronic diffuse liver diseases of non-viral etiology. Ultrasound and Functional Diagnostics. 2018(4):33-45. (In Russ.).

5. Colombo S, Buonocore M, Del Poggio A, Jamoletti C, Elia S, Mattiello M, et al. Head-to-head comparison of transient elastography (TE), real-time tissue elastography (RTE), and acoustic radiation force impulse (ARFI) imaging in the diagnosis of liver fibrosis. J Gastroenterol. 2012;47(4):461-9.

6. Cosgrove D, Piscaglia F, Bamber J, Bojunga J, Correas J-M, Gilja OH, et al. EFSUMB Guidelines and Recommendations on the Clinical Use of Ultrasound Elastography. P. 2: Clinical Applications. URL: http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0033-1335375.pdf?update=true. (Published online: 2013).

7. Osipov LV. Elastography technology in ultrasound diagnostics. Medical Alphabet. Diagnostic Radiology and Oncotherapy. 2013(3-4):5-21. (In Russ.)].

8. Rudenko OV, Safonov DV, Rykhtik PI, Gurbatov SN, Romanov SV. The physical bases of elastography. Compression elastography (Lecture. Part 1). Radiology-Practice. 2014(3):47-58. (In Russ.)].

9. Weskott H-P. Contrast sonography. Bremen: UNI-MED, 2014. 284 p. (In Russ.).

10. Claudon M, Dietrich CF, Choi BI, et al. Guidelines and good clinical practice recommendations for Contrast Enhanced Ultrasound (CEUS) in the liver—update 2012: A WFUMB-EFSUMB initiative in cooperation with representatives of AFSUMB, AIUM, ASUM, FLAUS and ICUS. Ultrasound Med Biol. 2013;39(2):187-210. DOI: 10.1016/j.ultrasmedbio.2012.09.002.

11. Claudon M, Dietrich CF, Choi BI, et al. Clinical recommendations for ultrasound examination of the liver using contrast agents. Revision from 2012 The WFUMB-EFSUMB initiative with the representation of ASUS, ASUS, ASUS, FLAUS and ICUS. Ed. by Mitkov VV. Ultrasound and Functional Diagnostics. 2017;(1):81-116 (In Russ.).

12. Yada N, Tamaki N, Koizumi Y, Hirooka M, Nakashima O, Hiasa Y, et al. Diagnosis of fibrosis and activity by a combined use of strain and shear wave imaging in patients with liver disease. Digest Dis. 2017;35(6):515-20. DOI: 10.1159/000480140.

13. Tikhankova AV, Borsukov AV, Buyeverov AO, Ivanov VV, Ivanov YuV. Improved Methods of the Contrast-Enhanced Ultrasound in Patient with Chronic Viral Hepatitis. Journal of Clinical Practice. 2019;10(1):4-9. DOI: 10.17816/clinpract1014-9 (In Russ.).

14. Borsukov AV, Buyeverov AO, Tikhankova AV. Capabilities of contrast-enhanced ultrasound in the diagnosis of liver cirrhosis. Medical Alphabet. Modern Functional Diagnostics. 2019;3(29(404)):26-30. (In Russ.). DOI: 10.33667/2078-5631-2019-3-29(404)-26-30.


Review

For citations:


Tikhankova A.V., Borsukov A.V., Buyeverov A.O., Bezmenova T.S., Gladarevskij K.A. The Capabilities of the Combi-Elasto and CEUS Ultrasound modes in the Diagnosis of Viral Hepatitis B. Journal of oncology: diagnostic radiology and radiotherapy. 2020;3(3):75-82. (In Russ.) https://doi.org/10.37174/2587-7593-2020-3-3-75-82

Views: 876


Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 License.


ISSN 2587-7593 (Print)
ISSN 2713-167X (Online)