Radiotherapy of Patients with Limited Brain Metastases
https://doi.org/10.37174/2587-7593-2018-1-1-7-14
Abstract
Brain metastases represent the first cause of malignant brain tumor. Without radiation therapy, prognosis was poor with fast neurological deterioration, and a median overall survival of one month. Nowadays, therapeutic options depend on brain metastases presentation, extra brain disease, performance status. Therefore, for oligometastatic brain patients with a better prognosis, this therapeutic modality is controversial. In fact, whole-brain radiation therapy improves neurological outcomes, but it can also induce late neuro-cognitive sequelae for long-term survivors of brain metastases. Thus, in this strategy for preserving good cognitive functions, stereotactic radiation therapy is a promising treatment. Delivering precisely targeted radiation in few high-doses in one to four brain metastases, allows to reduce radiation damage to normal tissues and it should allow to decrease radiation-induced cognitive decline. In this paper, we will discuss about therapeutic strategies radiation therapy for limited brain metastases patients.
About the Authors
S. M. Banov
N.N. Burdenko National Scientific and Practical Center for Neurosurgery
Russian Federation
Moscow
Russian Federation
Moscow
A. V. Golanov
N.N. Burdenko National Scientific and Practical Center for Neurosurgery
Russian Federation
Moscow
Russian Federation
Moscow
E. R. Vetlova
N.N. Burdenko National Scientific and Practical Center for Neurosurgery
Russian Federation
Moscow
Russian Federation
Moscow
A. A. Durgaryan
N.N. Burdenko National Scientific and Practical Center for Neurosurgery
Russian Federation
Moscow
Russian Federation
Moscow
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Review
For citations:
Banov S.M., Golanov A.V., Vetlova E.R., Durgaryan A.A. Radiotherapy of Patients with Limited Brain Metastases. Journal of oncology: diagnostic radiology and radiotherapy. 2018;1(1):7-14. (In Russ.) https://doi.org/10.37174/2587-7593-2018-1-1-7-14
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