18F-FDG-PET/CT Imaging of Different Hystological Subtypes of Hodgkin Lymphoma
https://doi.org/10.37174/2587-7593-2019-2-3-58-62
Abstract
Purpose: Evaluation of 18F-FDG uptake in different histological subtypes of Hodgkin lymphoma; analysis of primary cases of Hodgkin lymphoma with low 18F-FDG avidity and researching of the causes of low tracer uptake in baseline PET-scan.
Material and methods: 131 baseline PET/CT scans of patients with Hodgkin disease was investigated.
Results: Nodular sclerosis was most 18F-FDG avid, nodular lymphoid predominant Hodgkin disease had lowest 18F-FDG avidity, but these differences doesn’t allow to distinguish histological subtypes of Hodgkin lymphoma basing on 18F-FDG uptake properties. Tumor burden in patients with B-symptoms had a highest levels of 18F-FDG uptake.
Conclusion: 4 % of Hodgkin lymphoma is non-avid for 18F-FDG at baseline. It can be explained with severe immunodeficiency or indolent disease pattern.
About the Authors
A. S. Subbotin
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation
Russian Federation
Moscow
M. B. Dolgushin
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation
Russian Federation
Moscow
N. G. Afanasjeva
Chelyabinsk Regional Center of Oncology and Nuclear Medicine;South-Ural State Medical University
Russian Federation
Russian Federation
D. I. Nevzorov
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation
Russian Federation
Moscow
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Review
For citations:
Subbotin A.S., Dolgushin M.B., Afanasjeva N.G., Nevzorov D.I. 18F-FDG-PET/CT Imaging of Different Hystological Subtypes of Hodgkin Lymphoma. Journal of oncology: diagnostic radiology and radiotherapy. 2019;2(3):58-62. (In Russ.) https://doi.org/10.37174/2587-7593-2019-2-3-58-62
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