Renal Oncocytoma — Multifaces Appearances
N. Ts.‑D. Drobot,
X. A. Romanova,
E. S. Topalov,
S. D. Beghanova,
A. V. Klimov,
B. M. Medvedeva,
A. B. Lukianchenko https://doi.org/10.37174/2587-7593-2026-9-2-37-44
Abstract
Introduction: The effectiveness of adjuvant radiation therapy used to consolidate the effect of chemotherapy in patients with
Purpose: To familiarize readers with the diverse imaging features of renal oncocytomas as seen on 4-phase CT/MRI contrast-enhanced study.
Materials and methods: This article is based on one of the largest clinical data, reflecting the wide variety of imaging features of renal oncocytoma in 61 patients who underwent preoperative 4-phase CT/MRI contrast-enhanced study of the abdomen, followed by surgical intervention (resection or nephrectomy) and morphological examination of the resected specimens.
Results: The significant diversity in the imaging patterns of oncocytomas depends on the heterogeneity of their morphological structure: marked differences in tumor cellularity, the volume of stroma, and the presence of hemorrhagic and/or cystic elements. This is why their imaging manifistations can overlap with the features of various types of renal cell carcinoma (clear cell, chromophobe cell, etc.), which significantly complicates the accurate preoperative diagnosis of oncocytoma using standard imaging methods (ultrasound, CT, MRI). The well-known and characteristic oncocytoma’s pattern “a spoke-wheel-like enhancement” we observed in only 4 of 61 patients.
Conclusion: Differential diagnosis between oncocytoma and renal cell carcinoma based on CT/MRI findings can be extremely difficult in most cases, but is still possible in a few patients.
About the Authors
N. Ts.‑D. Drobot
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation
Competing Interests:
Russian Federation
Natalia Ts.‑D. Drobot
23 Kashirskoye Highway, Moscow, 115522
Competing Interests:
The authors declare no conflict of interest
X. A. Romanova
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation
Competing Interests:
Russian Federation
Xenia A. Romanova
23 Kashirskoye Highway, Moscow, 115522
Competing Interests:
The authors declare no conflict of interest
E. S. Topalov
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation
Competing Interests:
Russian Federation
Еugeniy S. Topalov
23 Kashirskoye Highway, Moscow, 115522
Competing Interests:
The authors declare no conflict of interest
S. D. Beghanova
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation
Competing Interests:
Russian Federation
Svetlana D. Beghanova
23 Kashirskoye Highway, Moscow, 115522
Competing Interests:
The authors declare no conflict of interest
A. V. Klimov
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation
Competing Interests:
Russian Federation
Alexey V. Klimov
23 Kashirskoye Highway, Moscow, 115522
Competing Interests:
The authors declare no conflict of interest
B. M. Medvedeva
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation
Competing Interests:
Russian Federation
Bela M. Medvedeva
23 Kashirskoye Highway, Moscow, 115522
Competing Interests:
The authors declare no conflict of interest
A. B. Lukianchenko
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation
Competing Interests:
Russian Federation
Alexander B. Lukianchenko
23 Kashirskoye Highway, Moscow, 115522
Competing Interests:
The authors declare no conflict of interest
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Review
For citations:
Drobot N.Ts., Romanova X.A., Topalov E.S., Beghanova S.D., Klimov A.V., Medvedeva B.M., Lukianchenko A.B. Renal Oncocytoma — Multifaces Appearances. Journal of oncology: diagnostic radiology and radiotherapy. 2026;9(2):37-44. (In Russ.) https://doi.org/10.37174/2587-7593-2026-9-2-37-44
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