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Implementation of Quality Assurance Protocols in the Radiotherapy Department of N.N. Blokhin National Medical Research Center of Oncology

https://doi.org/10.37174/2587-7593-2026-9-2-9-14

Abstract

Purpose: To develop and implement clinical radiotherapy protocols at the aimed at standardizing all stages of the treatment process and improving the quality of radiotherapy care.

Materials and methods: As part of the federal program “Fight Against Oncological Diseases,” a large-scale equipment upgrade was carried out, requiring revision of treatment planning approaches and staff training. The developed protocols cover the entire radiotherapy workflow — from CT simulation to treatment delivery — and include detailed recommendations for target volume delineation, organs-at-risk definition, dose constraints, and treatment plan quality criteria. Based on international standards (IAEA, ICRU, RTOG, TG 263), unified structure nomenclature, color coding, and dosimetric evaluation criteria were implemented.

Results: The implementation of 157 clinical protocols enabled acceleration of the treatment planning process, reduction of inter-observer variability, and improvement in the reproducibility of treatment outcomes. Standardization of clinical workflows contributed to reducing the probability of errors, simplifying the training of new staff members, and creating conditions for the automation of several procedures. The introduction of clinical protocols into radiation oncology practice improved the quality and safety of radiotherapy, enhanced team coordination, and contributed to better clinical outcomes for patients.

About the Authors

M. V. Chernykh
N.N. Blokhin National Medical Research Center of Oncology; I.M. Sechenov First Moscow State Medical University
Russian Federation

Marina V. Chernykh

24 Kashirskoye Highway, Moscow, 115478

8 Trubetskaya str., Moscow, 119048


Competing Interests:

The authors declare no conflict of interest



O. A. Mironova
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation

Olesia A. Mironova

24 Kashirskoye Highway, Moscow, 115478


Competing Interests:

The authors declare no conflict of interest



V. A. Ivanov
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation

Valery A. Ivanov

24 Kashirskoye Highway, Moscow, 115478


Competing Interests:

The authors declare no conflict of interest



A. S. Uvarov
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation

Andrey S. Uvarov

24 Kashirskoye Highway, Moscow, 115478


Competing Interests:

The authors declare no conflict of interest



V. D. Chernykh
Russian University of Medicine
Russian Federation

Vasili D. Chernykh

4 Dolgorukovskaya str., Moscow, 127006


Competing Interests:

The authors declare no conflict of interest



I. S. Stilidi
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation

Ivan S. Stilidi

24 Kashirskoye Highway, Moscow, 115478


Competing Interests:

The authors declare no conflict of interest



References

1. The Federal Project “Fighting Cancer” for the period 2019-2024, 2024 (In Russ.).

2. Transition from 2-D radiotherapy to 3-D conformal and intensity modulated radiotherapy IAEA-TECDOC-1588, 2008

3. Saiful Huq M, Fraass BA, Dunscombe PB, et al. The Report of Task Group 100 of the AAPM: Application of Risk Analysis Methods to Radiation Therapy Quality Management. Medical Physics. 2016; 43(7):4209-4262. https://doi.org/10.1118/1.4947547

4. Order No. 116n of the Ministry of Health of the Russian Federation dated February 19, 2021, “On Approval of the Procedure for Providing Medical Care to Adults with Cancer”, 2021. (In Russ.).

5. Safety Reports Series № 17 «Lessons learned from accidental expo­sures in radiotherapy» International Atomic Energy Agency, 2000.

6. Malignant Tumors: Practical Recommendations of the Russian Society of Clinical Oncology. Ed by Moiseenko VM. Moscow: Russian Society of Clinical Oncology, 2024. (In Russ.).

7. ICRU Report 83 Prescribing, Recording, and Reporting Photon-beam Intensity-modulated Radiation Therapy (IMRT). Journal of the ICRU. 2010;10(1). https://doi.org/ 10.1093/jicru/ndq001

8. Kachnic LA, Winter K, Myerson RJ. RTOG 0529: a phase 2 evalua­tion of dose-painted intensity modulated radiation therapy in com­bination with 5-fluorouracil and mitomycin-C for the reduction of acute morbidity in carcinoma of the anal canal. Int J Radiation On­cology Biol Phys. 2013; 86(1):27-33. https://doi.org/10.1016/j.ijrobp.2012.09.023

9. Bradley JD, Hu Ch, Komaki R. Long-Term Results of NRG Oncology RTOG 0617: Standard- Versus High-Dose Chemoradiotherapy With or Without Cetuximab for Unresectable Stage III Non-Small-Cell Lung Cancer. . 2019;38(7). Journal of Clinical Oncology https://doi.org/10.1200/JCO.19.01162

10. Bradley JD, Hu C, Komaki RR, et al. Long-Term Results of NRG Oncolo­gy RTOG 0617: Standard- Versus High-Dose Chemoradiotherapy With or Without Cetuximab for Unresectable Stage III Non-Small-Cell Lung Cancer. J Clin Oncol. 2020;38(7):706-714. https://doi.org/10.1200/JCO.19.01162.

11. Hong TS, Moughan J, Garofalo MC, et al. NRG Oncology Radiation Therapy Oncology Group 0822: A Phase 2 Study of Preoperative Chemoradiation Therapy Using Intensity Modulated Radiation Ther­apy in Combination With Capecitabine and Oxaliplatin for Patients With Locally Advanced Rectal Cancer. Int J Radiat Oncol Biol Phys. 2015;93(1):29-36. https://doi.org/10.1016/j.ijrobp.2015.05.005.

12. Standardizing Nomenclatures in Radiation Oncology The Report of AAPM Task Group 263, 2018


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For citations:


Chernykh M.V., Mironova O.A., Ivanov V.A., Uvarov A.S., Chernykh V.D., Stilidi I.S. Implementation of Quality Assurance Protocols in the Radiotherapy Department of N.N. Blokhin National Medical Research Center of Oncology. Journal of oncology: diagnostic radiology and radiotherapy. 2026;9(2):9-14. (In Russ.) https://doi.org/10.37174/2587-7593-2026-9-2-9-14

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ISSN 2587-7593 (Print)
ISSN 2713-167X (Online)