Comparative Analysis of PET/CT with 68Ga-FAPI and 18F-FDG in the Diagnosis of Esophageal Cancer.

E. S. Koroleva; P. E. Tulin; O. Abu-Khaidar; A. А. Urtenova; I. A. Skripachev; V. V. Solomyany; A. V. Filimonov

doi:10.37174/2587-7593-2025-8-2-23-31

Comparative Analysis of PET/CT with 68Ga-FAPI and 18F-FDG in the Diagnosis of Esophageal Cancer.

E. S. Koroleva, P. E. Tulin, O. Abu-Khaidar, A. А. Urtenova, I. A. Skripachev, V. V. Solomyany, A. V. Filimonov

https://doi.org/10.37174/2587-7593-2025-8-2-23-31

Full Text:

PDF (Rus)

Generate QR code

Abstract

Purpose: To study the diagnostic value of PET/CT with ⁶⁸Ga-FAPI compared with ¹⁸F-FDG in evaluation of cancer extent of esophageal. Materials and methods: The study included 15 patients (10 men, 5 women) with esophageal cancer. All patients underwent PET/CT with ¹⁸F-FDG and ⁶⁸Ga-FAPI-04 from January to December 2024. Primary tumor, metastases in regional lymph nodes were evaluated by PET/CT with ⁶⁸Ga-FAPI-04 and ¹⁸F-FDG. Histological verification was performed in all cases. Results: PET/CT with ⁶⁸Ga-FAPI-04 demonstrated high level of visualization of metastases in regional lymph nodes. The method finds a little more metastasis in regional lymph nodes in comparison with PET/CT with ¹⁸F-FDG. Conclusion: PET/CT c ⁶⁸GA-FAPI-04 demonstrates promising results in evaluation of cancer extent of esophageal. Further studies on large cohorts of patients are necessary to clarify the role of PET/CT with FAPI-04 for various histological types of esophageal cancer.