The Role of 99mTc-MIBI Scintigraphy in the Diagnosis of Soft Tissue Sarcomas
https://doi.org/10.37174/2587-7593-2018-1-1-31-36
Abstract
Purpose: To determine the diagnostic and therapeutic prognostic possibilities of 99mTc-MIBI scintigraphy in the study of soft tissue sarcomas.
Material and methods: The study included 37 primary patients. All conducted two-phase 99mTc-MIBI scanning.
Results: It was defined the correlation between the level of accumulation of radiopharmaceuticals in the tumor from the degree of tumor differentiation. It was defined the relationship of the level of “washout” of the 99mTc-MIBI from the tumor before treatment and the degree of therapeutic pathomorphosis.
Conclusion: 1. The relationship between 99mTc-MIBI affinity to the tumor and degree of differentiation is weak (r = –0,2177, p < 0.05).
2. The relationship between the rate of 99mTc-MIBI “washout” from the tumor and chemotherapy response is weak (r = –0,1964, p <0.05).
About the Authors
A. S. Krylov
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation
Moscow
Russian Federation
Moscow
A. D. Ryzhkov
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation
Moscow
Russian Federation
Moscow
Ja. A. Shchipakhina
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation
Moscow
Russian Federation
Moscow
S. V. Shiryaev
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation
Moscow
Russian Federation
Moscow
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Review
For citations:
Krylov A.S., Ryzhkov A.D., Shchipakhina J.A., Shiryaev S.V. The Role of 99mTc-MIBI Scintigraphy in the Diagnosis of Soft Tissue Sarcomas. Journal of oncology: diagnostic radiology and radiotherapy. 2018;1(1):31-36. (In Russ.) https://doi.org/10.37174/2587-7593-2018-1-1-31-36
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