Primary Radiodiagnosis of Skeletal Changes in the Onset of Multiple Myeloma, Approaches to Differential Radiodiagnosis (Observations from Practice)
https://doi.org/10.37174/2587-7593-2024-7-2-55-62
Abstract
Multiple myeloma — Rustitzky-Kahler disease is the most common tumor of the group of Ig-secreting lymphomas. The article presents the difficulties of radiodiagnosis assessment of skeletal changes in the initial stages of multiple myeloma, when bone pain is the only clinical manifestation, and X-ray examination reveals single large foci of destruction. These observations emphasize the important role of assessment and interpretation of bone changes in such situations, which can be the main guiding factor in choosing an examination algorithm for making a correct diagnosis. The article is of interest to radiation diagnosticians, it presents literature data and issues of differential radiodiagnosis of skeletal changes in multiple myeloma.
About the Authors
A. V. Laryukov
M.Z. Sigal Republic Clinical Oncology Dispensary; Kazan State Medical Academy; Kazan State Medical University
Russian Federation
Competing Interests:
Russian Federation
Andrey V. Laryukov.
31, Sibirskij trakt, Kazan', 420029; 36, Butlerova str., Kazan', 420012; 49, Butlerova str., Kazan', 420012
Tel.: 8-9600-32-42-96
Competing Interests:
None
E. K. Laryukova
M.Z. Sigal Republic Clinical Oncology Dispensary; Kazan State Medical Academy
Russian Federation
Competing Interests:
Russian Federation
Elena K. Laryukova.
31, Sibirskij trakt, Kazan', 420029; 36, Butlerova str., Kazan', 420012
Competing Interests:
None
F. F. Gubaidullina
M.Z. Sigal Republic Clinical Oncology Dispensary
Russian Federation
Competing Interests:
Russian Federation
Farida F. Gubaidullina.
31, Sibirskij trakt, Kazan’, 420029
Competing Interests:
None
Z. F. Mazitova
M.Z. Sigal Republic Clinical Oncology Dispensary
Russian Federation
Competing Interests:
Russian Federation
Zulfiya F. Mazitova.
31, Sibirskij trakt, Kazan’, 420029
Competing Interests:
None
References
1. Mendeleeva LP, Votjakova OM, Pokrovskaja OS. National clinical guidelines for the diagnosis and treatment of multiple myeloma. Hematology and Transfusiology. 2016;61/1.2:1-24. (In Russ.).
2. Markina YuYu. Skeletal lesions in myeloma and their radiation diagnosis. Siberian Medical Journal. 2008;3.(2):19-23. (In Russ.).
3. Dunopoulos M, Kyse R, Ferrnand J. Consensus recommendations for standard investigative workup:report of the international myeloma workshop consensus. Panel 3. 2011;117(18). 4701-5.
4. Mendeleeva LP, Votjakova OM, Rehtina IG. Russian clinical guidelines for the diagnosis and treatment of malignant lymphoproliferative diseases. Ed by Poddubnaya IV, Savchenko VG. Moscow. 2018;213-41. (In Russ.).
5. Bessmyl'cev OS, Abdukadyrov KL. Multiple Myeloma. Current View of the Problem. Almaty. 2007;117. (In Russ.).
6. Vojcehovskij VV, Landyshev YuS, Grigorenko AA. Multiple myeloma. Modern principles of Diagnosis and Treatment. Blagoveshhensk. 2012. 140 p. (In Russ.).
7. Stamo AP, Grigor'eva NV. Clinical charecteristics of pain syndrome in patients with multiple myeloma. S.S.Korsakov Journal of Neurology and Psychiatry. 2016;116(10):11-5. (In Russ.).
8. Bessmyl'cev OS. Multiple myeloma. Bulletin of Hematology. 2014;10(3):6-40. (In Russ.).
9. Rejnberg SA. X-ray diagnostics of bones and joints diseases. Moskva. 1964. 532 p. (In Russ.).
10. Mostovoi VP, Kislyakov VV, Kozii SL, Muravskaya UV. Osteosclerotic variant of myeloma. Controversial issues of medical tactics. Crimean Therapeutic Journal 2012;(2):16-7. (In Russ.).
11. Musaev AI, Ishanova AM. Possibilities of radiography in the diagnosis of myeloma. Bulletin of Medical Internet Conferences. 2019;9(8):316. (In Russ.).
12. Kostina IE, Gitis MK, Mendeleeva LP. Computed tomography in the diagnosis and monitoring of bone lesions in multiple myeloma using low-dose and standard scanning protocols. Hematology and Transfusiology. 2018;(2):113 (In Russ.).
13. Dutoit J, Verstraete K. MRI in multiple myeloma: a pictorial review of diagnostic and posttreatment findings. Insights into Imaging. 2016;7(4):553-69.
14. Durie B, Salmon S. A clinical staging system for multiple myeloma: correlation of measured myeloma cell mass with presenting clinical features, response to treatment and survival. Cancer. 1975;36:842-54.
15. Greipp PR. International staging system for multiple myeloma. Journal Clinical Oncology. 2005:23.15.3412-20.
16. Mihajlov MK, Volodina GI, Laryukova EK. Differential X-ray diagnostics of bone and joint diseases. Leningrad. 1985. 139 p. (In Russ.).
Review
For citations:
Laryukov A.V., Laryukova E.K., Gubaidullina F.F., Mazitova Z.F. Primary Radiodiagnosis of Skeletal Changes in the Onset of Multiple Myeloma, Approaches to Differential Radiodiagnosis (Observations from Practice). Journal of oncology: diagnostic radiology and radiotherapy. 2024;7(2):55-62. (In Russ.) https://doi.org/10.37174/2587-7593-2024-7-2-55-62
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