Oligodendroglioma of the Brain with a Gliomatous Growth Pattern Mimicking the Radiologic Features of Autoimmune Encephalitis
https://doi.org/10.37174/2587-7593-2023-6-3-72-80
Abstract
In this case report of a patient with verified oligodendroglioma with gliomatous growth pattern, at primary clinical and magnetic resonance (MR) diagnosis, the diagnosis of autoimmune encephalitis (AE) was proposed due to the presence of certain radiological patterns typically seen in AE. Further investigation, including advanced MR methods such as magnetic resonance spectrometry, suggested a possible diffuse multifocal glial involvement, which was further confirmed by histological and immunohistochemical examination. The comprehensive approach of evaluating dynamic MRI data, clinical presentation and the use of extended MRI protocols may assist in precise determination of neoplastic changes in the brain tissue.
About the Authors
M. B. Dolgushin
Federal Center of Brain Research and Neurotechnologies
Russian Federation
Russian Federation
1, p. 10, Ostrovityanova street, Moscow, 117513
O. I. Patsap
Federal Center of Brain Research and Neurotechnologies
Russian Federation
Russian Federation
1, p. 10, Ostrovityanova street, Moscow, 117513
O. V. Boiko
Federal Center of Brain Research and Neurotechnologies
Russian Federation
Russian Federation
1, p. 10, Ostrovityanova street, Moscow, 117513
A. R. Kabaeva
Federal Center of Brain Research and Neurotechnologies
Russian Federation
Russian Federation
1, p. 10, Ostrovityanova street, Moscow, 117513
R. V. Nadelyaev
Federal Center of Brain Research and Neurotechnologies
Russian Federation
Russian Federation
1, p. 10, Ostrovityanova street, Moscow, 117513
References
1. Sanson M, Napolitano M, Cartalat-Carel S. La gliomatose cérébrale [Gliomatosis cerebri]. Rev Neurol (Paris). 2005 Feb;161(2):173-81. French. doi: 10.1016/s0035-3787(05)85020-9.
2. Louis DN, Perry A, Reifenberger G. The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary. Acta Neuropathol. 2016 Jun;131(6):803-20. doi: 10.1007/s00401-016-1545-1.
3. Oyanguren B, Sánchez V, González FJ. Limbic encephalitis: a clinical-radiological comparison between herpetic and autoimmune etiologies. Eur J Neurol. 2013 Dec;20(12):1566-70. doi: 10.1111/ene.12249.
4. Kelley BP, Patel SC, Marin HL. Autoimmune Encephalitis: Pathophysiology and Imaging Review of an Overlooked Diagnosis. AJNR Am J Neuroradiol. 2017 Jun;38(6):1070-1078. doi: 10.3174/ajnr.A5086.
5. del Carpio-O'Donovan R, Korah I, Salazar A. Gliomatosis cerebri. Radiology. 1996 Mar;198(3):831-5. doi: 10.1148/radiology.198.3.8628879.
6. Abboud H, Probasco JC, Irani S; Autoimmune Encephalitis Alliance Clinicians Network. Autoimmune encephalitis: proposed best practice recommendations for diagnosis and acute management. J Neurol Neurosurg Psychiatry. 2021 Jul;92(7):757-768. doi: 10.1136/jnnp-2020-325300.
7. Schwartz RB, Mantello MT. Primary brain tumors in adults. Semin Ultrasound CT MR. 1992 Dec;13(6):449-72. PMID: 1489557.
8. Dalmau J, Graus F, Villarejo A. Clinical analysis of anti-Ma2-associated encephalitis. Brain. 2004 Aug;127(Pt 8):1831-44. doi: 10.1093/brain/awh203.
9. Gaillard F, Knipe H, Mannina D, et al. Oligodendroglioma. Reference article, Radiopaedia.org (Accessed on 28 May 2023. doi: 10.53347/rID-1772
10. Jenkinson MD, du Plessis DG, Smith TS. Histological growth patterns and genotype in oligodendroglial tumours: correlation with MRI features. Brain. 2006 Jul;129(Pt 7):1884-91. doi: 10.1093/brain/awl108.
11. IŞik N, Candan F, Dincer A. Serial cranial MR imaging and single voxel proton MR spectroscopy in paraneoplastic limbic encephalitis., 2004; 50(1), 0–7. doi:10.1016/j.ejrex.2003.12.005
12. Bendszus M, Warmuth-Metz M, Klein R. MR spectroscopy in gliomatosis cerebri. AJNR Am J Neuroradiol. 2000 Feb;21(2):375-80. PMID: 10696026; PMCID: PMC7975356.
13. Guzmán-de-Villoria JA, Sánchez-González J, Muñoz L. 1H MR spectroscopy in the assessment of gliomatosis cerebri. AJR Am J Roentgenol. 2007 Mar;188(3):710-4. doi: 10.2214/AJR.06.0055.
14. Koeller KK, Rushing EJ. From the archives of the AFIP: Oligodendroglioma and its variants: radiologic-pathologic correlation. Radiographics. 2005 Nov-Dec;25(6):1669-88. doi: 10.1148/rg.256055137.
15. Al-Okaili RN, Krejza J, Wang S. Advanced MR imaging techniques in the diagnosis of intraaxial brain tumors in adults. Radiographics. 2006 Oct;26 Suppl 1:S173-89. doi: 10.1148/rg.26si065513.
16. Graus F, Titulaer MJ, Balu R. A clinical approach to diagnosis of autoimmune encephalitis. Lancet Neurol. 2016 Apr;15(4):391-404. doi: 10.1016/S1474-4422(15)00401-9.
Review
For citations:
Dolgushin M.B., Patsap O.I., Boiko O.V., Kabaeva A.R., Nadelyaev R.V. Oligodendroglioma of the Brain with a Gliomatous Growth Pattern Mimicking the Radiologic Features of Autoimmune Encephalitis. Journal of oncology: diagnostic radiology and radiotherapy. 2023;6(3):72-80. (In Russ.) https://doi.org/10.37174/2587-7593-2023-6-3-72-80
Views:
286
Email this article 