Possibilities of Diffusion-Weighted MRI in Clarification of the Degree of Malignance of Recurrent Retroperitoneal Liposarcomas
https://doi.org/10.37174/2587-7593-2022-5-4-43-53
Abstract
Purpose: The aim of our study was to study the possibilities of DW-MRI in the differential diagnosis of recurrent retroperitoneal highly differentiated and dedifferentiated liposarcomas (WLS and DLS respectively).
Material and methods: The study is based on the data of a retrospective study of 36 patients who underwent surgery on for retroperitoneal highly differentiated (n = 27) and dedifferentiated liposarcomas (n = 9). All patients received MRI of the abdominal cavity and pelvis without intravenous contrast enhancement with further assessment of size, shape, contours and structure. When analyzing DW-MRI and ADC maps, small soft tissue nodes were evaluated.
Results: Morphological studies were performed in all patients. The results of the qualitative analysis showed statistically significant differences in the differential diagnosis of WLS recurrences from DPS in the presence of septa and pseudocapsule (p = 0.0032 and p = 0.0028, respectively). The results of the study demonstrated differences in the ADC values in the solid component of recurrent tumors of WLS and DLS: the median ADC values in the WLS group were higher (1960×10–6 mm2/s) than in the DLS group (1031×10–6 mm2/s). The sensitivity of this sign in the differential diagnosis of WLS from DLS was 87.5 %, the specificity was 70 %.
About the Authors
E. S. Kolobanova
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation
Competing Interests:
Russian Federation
115478, Moscow, Kashirskoye Highway, 24
Competing Interests:
Not declared.
B. M. Medvedeva
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation
Competing Interests:
Russian Federation
115478, Moscow, Kashirskoye Highway, 24
Competing Interests:
Not declared.
M. G. Lapteva
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation
Competing Interests:
Russian Federation
115478, Moscow, Kashirskoye Highway, 24
Competing Interests:
Not declared.
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Review
For citations:
Kolobanova E.S., Medvedeva B.M., Lapteva M.G. Possibilities of Diffusion-Weighted MRI in Clarification of the Degree of Malignance of Recurrent Retroperitoneal Liposarcomas. Journal of oncology: diagnostic radiology and radiotherapy. 2022;5(4):43-53. (In Russ.) https://doi.org/10.37174/2587-7593-2022-5-4-43-53
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