Shear Wave Ultrasonic Elastometry in Diagnostics of Metastatic Lymph Nodes in Neck Thyroid Cancer
https://doi.org/10.37174/2587-7593-2021-4-4-50-55
Abstract
Purpose: Determination of informative value of a new method of ultrasound tomography, based on the properties of elasticity of soft tissues, in the differential diagnosis of metastatic lesions of the lymph nodes of the neck thyroid cancer.
Material and methods: To assess the capabilities of shear wave ultrasound elastometry in the diagnosis of metastatic lesions of the lymph nodes in thyroid cancer, a study was carried out with 45 patients with suspected thyroid cancer. The work was performed by devices Acuson S2000 Siemens, Avius hi vision Hitachi using a linear sensor with a frequency of 5–12 MHz. For each object of the study, from 5 to 10 measurements of the shear wave velocity in m / s were made, depending on the size of the lymph nodes.
Results: Reliable results were obtained in the group of altered lymph nodes (statistical significance p < 0.05). Interquartile intervals and the most common values of shear wave velocities do not overlap: in metastases — 2.20– 3.36 m/s, with hyperplasia of lymph nodes — 0.70–1.88 m/s, and medians show a significant difference in velocities: metastases — 3.00 m/s, hyperplastic lymph nodes 1.38 m/s.
Conclusions: Shear wave elastography objectifies ultrasound studies, obtaining specific indicators of shear wave velocity in the areas of interest, and can be used as an additional diagnostic tool in the differential diagnosis of metastatic and hyperplastic lymph nodes.
About the Authors
E. A. Gudilina
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation
Russian Federation
24 Kashirskoye Highway, Moscow, 115478
T. Yu. Danzanova
N.N. Blokhin National Medical Research Center of Oncology; N.I. Pirogov Russian National Research Medical University (Pirogov Medical University)
Russian Federation
Russian Federation
24 Kashirskoye Highway, Moscow, 115478
1, 6 build., Ostrovityanova str., Moscow, 117437
P. I. Lepedatu
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation
Russian Federation
24 Kashirskoye Highway, Moscow, 115478
G. T. Sinyukova
N.N. Blokhin National Medical Research Center of Oncology
Russian Federation
Russian Federation
24 Kashirskoye Highway, Moscow, 115478
References
1. Сенча АН. Ультразвуковое исследование щитовидной железы. Шаг за шагом. От простого к сложному. Москва: МЕДпресс-информ, 2019. 208 с. [Sencha AN. Ultrasound examination of the thyroid gland. Step by step. From simple to complex. Moscow, 2019. 208 p (In Russian)].
2. Пачес АИ, Проп РМ. Рак щитовидной железы. 2-е изд, перераб. и доп. М.: Центр внедрения достижений науки и техники «Москва», 1994. 372 с. [Paches AI, Prop RM. Thyroid cancer. 2nd ed. Moscow, 1994. 372 p (In Russian)].
3. Каприн АД, Старинский ВВ, Петрова ГВ. Состояние онкологической помощи населению России в 2017 г. М.: МНИОИ им. П.А. Герцена, 2018. 236 с. [Caprin AD, Starinskiy VV, Petrova GV. The state of cancer care for the population of Russia in 2017. Moscow, 2018. 236 p (In Russian)]
4. Doherty JR, Trahey GE, Nightingale KR, Palmeri ML. Acoustic radiation force elasticity imaging in diagnostic ultrasound. IEEE Trans Ultrason Ferroelectr Freq Control. 2013;60(4):685-701. DOI: 10.1109/TUFFC.2013.2617
5. Rutherford GC, Franc B, O’Connor A. Nuclear medicine in the assessment of differentiated thyroid cancer. Clin Radiol. 2008 Apr; 63(4):453-63. Epub 2007 Nov 5. DOI: 10.1016/j.crad.2007.08.002
6. Furukawa MK, Kubota A, Hanamura H, Furukawa M. Clinical application of real-time tissue elastography to head and neck cancer-evaluation of cervical lymph node metastasis with real-time tissue elastography. Nippon Jibiinkoka Gakkai Kaiho. 2007;110.(7): 503-5 (In Japanese). DOI: 10.3950/jibiinkoka.110.503
7. Ковалева ЕВ, Данзанова ТЮ, Синюкова ГТ и др. Успешный опыт применения ультразвуковой эластографии в подходе к предварительной промежуточной оценке эффективности лечения больных лимфомой Ходжкина. Онкогематология. 2019;14(4):40-6. [Kovaleva EV, Danzanova TYu, Sinyukova GT, et al. Successful use of ultrasound elastography in the preliminary intermediate evaluation of therapeutic response in patients with Hodgkin’s lymphoma. Oncohematology. 2019;14(4):40-6 (In Russian)]. DOI: 10.17650/1818-8346-2019-14-4-40-46.
8. Ковалева ЕВ, Данзанова ТЮ, Синюкова ГТ и др. Успешный опыт применения ультразвуковой эластографии в дифференциальной диагностике измененных поверхностных лимфатических узлов при лимфоме и метастазах солидных опухолей. Онкогематология. 2020;15(2):25- 31 [Kovaleva EV, Danzanova TYu, Sinyukova GT, et al. Successful experience in the use of ultrasound elastography in the differentiating of lymphomatous and metastatic superficial lymphadenopathy. Oncohematology. 2020;15(2):25-31 (In Russian)]. DOI: 10.17650/1818-8346-2020-15-2-00-00.
9. Ковалева ЕВ, Данзанова ТЮ, Синюкова ГТ и др. Оценка возможностей точечной ультразвуковой эластографии в дифференциальной диагностике лимфопролиферативных и реактивных изменений поверхностных лимфатических узлов. Онкогематология. 2020;15(1):49-54 [Kovaleva EV, Danzanova TYu, Sinyukova GT, et al. Evaluation of the possibilities of shear wave elastography for differentiation of lymphomatous and reactive changes of superficial lymph nodes. Oncohematology. 2020;15(1):49-54 (In Russian)]. DOI: 10.17650/1818-8346-2020-15-1-00-00.
Review
For citations:
Gudilina E.A., Danzanova T.Yu., Lepedatu P.I., Sinyukova G.T. Shear Wave Ultrasonic Elastometry in Diagnostics of Metastatic Lymph Nodes in Neck Thyroid Cancer. Journal of oncology: diagnostic radiology and radiotherapy. 2021;4(4):50-55. (In Russ.) https://doi.org/10.37174/2587-7593-2021-4-4-50-55
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