Comparison of in vivo and ex vivo Elastography and Elastometric in the Diagnosis of Metastasis of Skin Melanoma to Peripheral Lymph Nodes
E. V. Tikhonova,
S. N. Berdnikov,
I. V. Samoylenko,
K. V. Orlova,
K. A. Baryshnikov,
V. V. Nazarova,
M. S. Makhotina,
A. D. Kuzmin,
A. S. Bredneva,
A. M. Kiseleva,
V. N. Sholokhov,
L. V. Demidov https://doi.org/10.37174/2587-7593-2025-8-2-65-72
Abstract
Purpose: To conduct a comparative analysis of the diagnostic effectiveness of elastography and elastometry in detecting melanoma metastases in lymph nodes using histological examination of a macropreparation as a reference method. The data obtained can help in the development of algorithms for noninvasive diagnostics and reduce the number of unjustified surgical interventions. Materials and methods: A prospective study of 14 macro-preparations of metastatically affected lymph nodes removed from patients with skin melanoma during elective surgical interventions was conducted. Conclusion: An integrated ultrasound approach combining elastography and elastometry demonstrates high accuracy in detecting metastatic lymph node lesions in skin melanoma.
About the Authors
E. V. Tikhonova
N.N. Blokhin National Medical Research Center of Oncology; 24 Kashirskoye Shosse
Russian Federation
Russian Federation
Elena V. Tikhonova
24 Kashirskoye Shosse, Moscow,115478
S. N. Berdnikov
N.N. Blokhin National Medical Research Center of Oncology; 24 Kashirskoye Shosse
Russian Federation
Russian Federation
I. V. Samoylenko
N.N. Blokhin National Medical Research Center of Oncology; 24 Kashirskoye Shosse
Russian Federation
Russian Federation
K. V. Orlova
N.N. Blokhin National Medical Research Center of Oncology; 24 Kashirskoye Shosse
Russian Federation
Russian Federation
K. A. Baryshnikov
N.N. Blokhin National Medical Research Center of Oncology; 24 Kashirskoye Shosse
Russian Federation
Russian Federation
V. V. Nazarova
N.N. Blokhin National Medical Research Center of Oncology; 24 Kashirskoye Shosse
Russian Federation
Russian Federation
M. S. Makhotina
N.N. Blokhin National Medical Research Center of Oncology; 24 Kashirskoye Shosse
Russian Federation
Russian Federation
A. D. Kuzmin
N.N. Blokhin National Medical Research Center of Oncology; 24 Kashirskoye Shosse
Russian Federation
Russian Federation
A. S. Bredneva
N.N. Blokhin National Medical Research Center of Oncology; 24 Kashirskoye Shosse
Russian Federation
Russian Federation
A. M. Kiseleva
N.N. Blokhin National Medical Research Center of Oncology; 24 Kashirskoye Shosse
Russian Federation
Russian Federation
V. N. Sholokhov
N.N. Blokhin National Medical Research Center of Oncology; 24 Kashirskoye Shosse
Russian Federation
Russian Federation
L. V. Demidov
N.N. Blokhin National Medical Research Center of Oncology; 24 Kashirskoye Shosse
Russian Federation
Russian Federation
References
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Review
For citations:
Tikhonova E.V., Berdnikov S.N., Samoylenko I.V., Orlova K.V., Baryshnikov K.A., Nazarova V.V., Makhotina M.S., Kuzmin A.D., Bredneva A.S., Kiseleva A.M., Sholokhov V.N., Demidov L.V. Comparison of in vivo and ex vivo Elastography and Elastometric in the Diagnosis of Metastasis of Skin Melanoma to Peripheral Lymph Nodes. Journal of oncology: diagnostic radiology and radiotherapy. 2025;8(2):65-72. (In Russ.) https://doi.org/10.37174/2587-7593-2025-8-2-65-72
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