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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ojrdrt</journal-id><journal-title-group><journal-title xml:lang="ru">Онкологический журнал: лучевая диагностика, лучевая терапия</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of oncology: diagnostic radiology and radiotherapy</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2587-7593</issn><issn pub-type="epub">2713-167X</issn><publisher><publisher-name>НЕКОММЕРЧЕСКОЕ ПАРТНЕРСТВО «ОБЩЕСТВО ИНТЕРВЕНЦИОННЫХ ОНКОРАДИОЛОГОВ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.37174/2587-7593-2019-2-3-88-94</article-id><article-id custom-type="elpub" pub-id-type="custom">ojrdrt-62</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ СЛУЧАИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASES</subject></subj-group></article-categories><title-group><article-title>Дифференциальная диагностика очага хронического остеомиелита рукоятки грудины у пациентки со злокачественной опухолью молочной железы (клиническое наблюдение)</article-title><trans-title-group xml:lang="en"><trans-title>Differential Diagnosis of Chronic Osteomyelitis in Manubrium of the Sternum in a Patient with Breast Cancer (Clinical Case)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ульянова</surname><given-names>Р. Х.</given-names></name><name name-style="western" xml:lang="en"><surname>Ulyanova</surname><given-names>R. Kh.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>St. Petersburg</p></bio><email xlink:type="simple">ulyanovaroksana@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мищенко</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Mishchenko</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>St. Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Черная</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Chernaya</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>St. Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Косичкина</surname><given-names>А. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Kosichkina</surname><given-names>A. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>St. Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Данилов</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Danilov</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>St. Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шипилова</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Shipilova</surname><given-names>А. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>St. Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бисярин</surname><given-names>М. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Bisyarin</surname><given-names>M. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Санкт-Петербург</p></bio><bio xml:lang="en"><p>St. Petersburg</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Национальный медицинский исследовательский центр онкологии им. Н.Н. Петрова Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>N.N. Petrov National Medical Research Oncology Center</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2019</year></pub-date><pub-date pub-type="epub"><day>30</day><month>09</month><year>2019</year></pub-date><volume>2</volume><issue>3</issue><fpage>88</fpage><lpage>94</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ульянова Р.Х., Мищенко А.В., Черная А.В., Косичкина А.Б., Данилов В.В., Шипилова А.А., Бисярин М.И., 2019</copyright-statement><copyright-year>2019</copyright-year><copyright-holder xml:lang="ru">Ульянова Р.Х., Мищенко А.В., Черная А.В., Косичкина А.Б., Данилов В.В., Шипилова А.А., Бисярин М.И.</copyright-holder><copyright-holder xml:lang="en">Ulyanova R.K., Mishchenko A.V., Chernaya A.V., Kosichkina A.B., Danilov V.V., Shipilova А.A., Bisyarin M.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.oncoradjournal.ru/jour/article/view/62">https://www.oncoradjournal.ru/jour/article/view/62</self-uri><abstract><p>Хронический остеомиелит представляет собой воспалительный процесс в кости, вызванный патогенными микроорганизмами, который приводит к разрушению кости и образованию секвестра.</p><p>В клиническом наблюдении представлен случай 58-летней женщины с верифицированной карциномой левой молочной железы, которой было проведено комплексное лечение в 2008-2009 гг., а в 2017 г. при контрольной остеосцинтиграфии выявлен подозрительный на метастаз очаг в левой половине рукоятки грудины. По результатам компьютерной томографии и остеосцинтиграфии, а также при неоднозначных результатах трепанобиопсии образования было принято решение о хирургическом лечении. При гистологическом исследовании оперативного материала изменения в грудине оказались проявлением хронического остеомиелита.</p><p>Случай интересен сложностью дифференциальной диагностики метастатического поражения при раке молочной железы и хронического остеомиелита по данным рентгеновской компьютерной томографии.</p></abstract><trans-abstract xml:lang="en"><p>Chronic osteomyelitis represents a progressive inflammatory process caused by pathogens, resulting in bone destruction and sequestrum formation.</p><p>A case of a 58-year-old woman with verified carcinoma of the left breast, which was treated in 2008-2009, is presented. In 2017, a focus suspicious of metastasis was detected in the left half of manubrium of the sternum by osteoscintigraphy. According to the changes in computed tomography and osteoscintigraphy, with ambiguous results of core biopsy, a decision to perform surgical treatment was made. A pathomorphological examination revealed chronic osteomyelitis of manubrium.</p><p>The case is interesting because of the complexity of the differential diagnosis of metastatic lesions in breast cancer and chronic osteomyelitis according to computed tomography.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>рак молочной железы</kwd><kwd>хронический остеомиелит</kwd><kwd>КТ</kwd><kwd>дифференциальная диагностика</kwd></kwd-group><kwd-group xml:lang="en"><kwd>breast cancer</kwd><kwd>chronic osteomyelitis</kwd><kwd>СТ</kwd><kwd>differential diagnosis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Parsons B., Strauss E. Surgical management of chronic osteomyelitis // Amer. J. Surg. 2004. Vol. 188. Suppl. 1A. 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