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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ojrdrt</journal-id><journal-title-group><journal-title xml:lang="ru">Онкологический журнал: лучевая диагностика, лучевая терапия</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of oncology: diagnostic radiology and radiotherapy</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2587-7593</issn><issn pub-type="epub">2713-167X</issn><publisher><publisher-name>НЕКОММЕРЧЕСКОЕ ПАРТНЕРСТВО «ОБЩЕСТВО ИНТЕРВЕНЦИОННЫХ ОНКОРАДИОЛОГОВ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.37174/2587-7593-2018-1-1-37-39</article-id><article-id custom-type="elpub" pub-id-type="custom">ojrdrt-38</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ЛУЧЕВАЯ ДИАГНОСТИКА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>DIAGNOSTIC RADIOLOGY</subject></subj-group></article-categories><title-group><article-title>Возможности МРТ с гепатотропным контрастным препаратом в диагностике гепатоцеллюлярного рака</article-title><trans-title-group xml:lang="en"><trans-title>Gadoxetic Acid-Enhanced MRI for the Detection of Hepatocellular Carcinoma</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Медведева</surname><given-names>Б. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Medvedeva</surname><given-names>B. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><email xlink:type="simple">m-diagnostica@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лукьянченко</surname><given-names>А. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Lukyanchenko</surname><given-names>A. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Москва</p></bio><email xlink:type="simple">m-diagnostica@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина Минздрава РФ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>N.N. Blokhin National Medical Research Center of Oncology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>30</day><month>03</month><year>2018</year></pub-date><volume>1</volume><issue>1</issue><fpage>37</fpage><lpage>39</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Медведева Б.М., Лукьянченко А.Б., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Медведева Б.М., Лукьянченко А.Б.</copyright-holder><copyright-holder xml:lang="en">Medvedeva B.N., Lukyanchenko A.B.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.oncoradjournal.ru/jour/article/view/38">https://www.oncoradjournal.ru/jour/article/view/38</self-uri><abstract><sec><title>Цель</title><p>Цель: Уточнение возможностей применения гепатоспецифического контрастного препарата гадоксетовой кислоты и методики диффузионно-взвешенной МРТ (ДВ-МРТ) в диагностике гепатоцеллюлярного рака (ГЦР).</p></sec><sec><title>Результаты</title><p>Результаты: На основании полученных нами данных был выявлен комплекс семиотических признаков, позволяющих наиболее корректно дифференцировать гепатоцеллюлярный рак:</p></sec><sec><title>Выводы</title><p>Выводы: Комплекс семиотических признаков, основанных на применении гепатотропного контрастного препарата гадоксетовой кислоты в сочетании с методикой ДВ-МРТ, позволяет уверенно распознавать ГЦР среди других новообразований печени (чувствительность 100 %, специфичность 91,7 %, точность 97,1 %).</p></sec></abstract><trans-abstract xml:lang="en"><p>To specify the possibilities for application of the liver-specific contrast agent (gadoxetic acid) in MRI with diffusion-weighted images (DWI) in the diagnosis of hepatocellular carcinoma (HCC).</p><sec><title>Results</title><p>Results: On the basis of the data obtained, we identified a complex of semiotic features that allow the tumor to be correctly differentiated as a HCC, namely:</p></sec><sec><title>Conclusions</title><p>Conclusions: The complex of revealed semiotic features based on the combination of the liver-specific contrast agent (gadoxetic acid) in MRI with DWI makes it possible to reliably recognize the HCC among other neoplasms of the liver (sensitivity 100 %, specificity 91.7 %, accuracy 97.1 %).</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>магнитно-резонансная томография</kwd><kwd>гепатотропные контрастирующие препараты</kwd><kwd>гепатоцеллюлярный рак</kwd></kwd-group><kwd-group xml:lang="en"><kwd>MRI</kwd><kwd>hepatotropic contrast agents</kwd><kwd>hepatocellular carcinoma</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Лукьянченко А.Б., Медведева Б.М., Шабанов М.а. и соавт. 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