ojrdrtОнкологический журнал: лучевая диагностика, лучевая терапияJournal of oncology: diagnostic radiology and radiotherapy2587-75932713-167XНЕКОММЕРЧЕСКОЕ ПАРТНЕРСТВО «ОБЩЕСТВО ИНТЕРВЕНЦИОННЫХ ОНКОРАДИОЛОГОВ»10.37174/2587-7593-2018-1-3-44-48ojrdrt-33Research ArticleЛУЧЕВАЯ ДИАГНОСТИКАDIAGNOSTIC RADIOLOGYДиффузионно-взвешенная магнитно-резонансная томография всего тела с оценкой измеряемого коэффициента диффузии при лимфоме ХоджкинаWhole-Body Diffusion-Weighted Magnetic Resonance Imaging with Assessment of Apparent Diffusion Coefficient in Hodgkin’s LymphomaМихайловА. И.MikhaylovA. I.mdnadya@gmail.comПановВ. О.PanovV. O.mdnadya@gmail.comМещеряковаН. А.MeshcheryakovaN. A.mdnadya@gmail.comПронинА. И.ProninA. I.mdnadya@gmail.comВихроваН. Б.VikhrovaN. B.mdnadya@gmail.comДолгушинМ. Б.DolgushinM. B.mdnadya@gmail.comРоссийская медицинская академия непрерывного последипломного образования Минздрава РФ; Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина Минздрава РФРоссияRussian Medical Academy of Continuing Postgraduate Education; N.N. Blokhin National Medical Research Center of OncologyRussian FederationРоссийская медицинская академия непрерывного последипломного образования Минздрава РФРоссияRussian Medical Academy of Continuing Postgraduate EducationRussian FederationНациональный медицинский исследовательский центр онкологии им. Н.Н. Блохина Минздрава РФРоссияN.N. Blokhin National Medical Research Center of OncologyRussian Federation201830092018134448Copyright © Михайлов А.И., Панов В.О., Мещерякова Н.А., Пронин А.И., Вихрова Н.Б., Долгушин М.Б., 20182018Михайлов А.И., Панов В.О., Мещерякова Н.А., Пронин А.И., Вихрова Н.Б., Долгушин М.Б.Mikhaylov A.I., Panov V.O., Meshcheryakova N.A., Pronin A.I., Vikhrova N.B., Dolgushin M.B.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.oncoradjournal.ru/jour/article/view/33Цель

Цель: Определить возможность применения метода диффузно-взвешенной МРТ с определением измеряемого коэффициента (ИКД) для дифференциальной диагностики нормальных лимфатических узлов (ЛУ) от пораженных ЛУ у пациентов с лимфомой Ходжкина (ЛХ).

Материал и методы

Материал и методы: Для определения эффективности использования ИКД с целью дифференциации нормальных и пораженных ЛУ при ЛХ проведено сравнение значений ИКД ЛУ у 27 условно здоровых лиц и у 41 пациента с верифицированным диагнозом ЛХ.

Результаты

Результаты: Построение 95 %-х доверительных интервалов показало, что значения ИКД нормальных ЛУ находились в интервале от 1,00 до 1,73.10–3 мм2/с и были достоверно выше (p < 0,05), чем у ЛУ, пораженных лимфоматозным процессом (ИКД от 0,59 до 0,94.10–3 с/мм2). Порог дискриминации нормальных и лимфоматозно-измененных ЛУ находился в интервале от 0,94 до 1,00.10–3 мм2/с. Таким образом ЛУ, имеющие ИКД ниже 0,94.10–3 мм2/с, можно считать пораженными лимфоматозным процессом.

Purpose

Purpose: To determine the effectiveness of apparent diffusion coefficient (ADC) for the purpose of normal and diseased lymph nodes (LN) differentiation in HL by DWI MRI.

Material and methods

Material and methods: To determine the effectiveness of ADC for the purpose of normal and diseased LN differentiation in HL was compared ADC values of LN in 27 apparently healthy individuals and in 41 patients with verified HL.

Results

Results: 95 % confidence intervals showed that values of ADC in normal LN ranged from 1.00 to 1.73 . 10–3 s/mm2 and were significantly higher (p < 0,05), than in LN affected by HL (ADC from 0.59 to 0.94 . 10–3 mm2/s). Cut off point of normal and lymphomatous-LN ranged from 0.94 to 1.00 . 10–3 mm2/s. Therefore, LN with ADC below 0.94 . 10–3 mm2/s could be interpreted as affected by HL.

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The authors declare that there are no conflicts of interest present.