ojrdrtОнкологический журнал: лучевая диагностика, лучевая терапияJournal of oncology: diagnostic radiology and radiotherapy2587-75932713-167XНЕКОММЕРЧЕСКОЕ ПАРТНЕРСТВО «ОБЩЕСТВО ИНТЕРВЕНЦИОННЫХ ОНКОРАДИОЛОГОВ»10.37174/2587-7593-2023-6-3-9-23ojrdrt-311Research ArticleЛУЧЕВАЯ ТЕРАПИЯRADIOTHERAPYСтереотаксическое облучение новообразований спинальной локализации. Обзор литературы и опыт НМИЦ нейрохирургии им. ак. Н.Н. Бурденко Минздрава России. Часть 1: Радиохирургическое лечение доброкачественных первичных опухолей и сосудистых мальформаций спинного мозга и позвоночникаStereotactic Irradiation of Neoplasms of Spinal Localization. Literature Review and Experience of N.N. Burdenko Neurosurgical Center. Part 1. Radiosurgical Treatment of Benign Primary Tumors and Vascular Malformations of the Spinal Cord and Spinehttps://orcid.org/0000-0002-0976-4547ГолановА. В.GolanovA. V.

 Голанов Андрей Владимирович  — д.м.н., профессор,член-корреспондент РАН, заведующий отделением радиотерапии 

Москва 125047, ул. Тверская-Ямская, 16

125993 Москва, ул. Баррикадная, 2/1, стр. 1

16, Tverskaya-Yamskaya str., Moscow, 125047

2/1, p. 1, Barricadnaya str., Moscow, 125993

golanov@nsi.ruhttps://orcid.org/0000-0003-3470-5802АнтипинаН. А.AntipinaN. A.

 Москва 125047, ул. Тверская-Ямская, 16

16, Tverskaya-Yamskaya str., Moscow, 125047

https://orcid.org/0000-0002-4904-0324ВетловаЕ. Р.VetlovaE. R.

 Москва 125047, ул. Тверская-Ямская, 16

16, Tverskaya-Yamskaya str., Moscow, 125047

https://orcid.org/0000-0001-8893-3830ЗолотоваС. В.ZolotovaS. V.

 Москва 125047, ул. Тверская-Ямская, 16

16, Tverskaya-Yamskaya str., Moscow, 125047

https://orcid.org/0000-0002-1436-0010ГалкинМ. В.GalkinM. V.

16, Tverskaya-Yamskaya str., Moscow, 125047

https://orcid.org/0009-0005-1143-2030ЛестроваяА. И.LestrovayaA. I.

 Москва 125047, ул. Тверская-Ямская, 16

16, Tverskaya-Yamskaya str., Moscow, 125047

Национальный медицинский исследовательский центр нейрохирургии им. ак. Н.Н. Бурденко Минздрава; Российская медицинская академия непрерывного профессионального образования Минздрава РоссииРоссияN.N. Burdenko Neurosurgical Center; Russian Medical Academy of Continuous Professional EducationRussian FederationНациональный медицинский исследовательский центр нейрохирургии им. ак. Н.Н. Бурденко МинздраваРоссияN.N. Burdenko Neurosurgical CenterRussian Federation20230910202363923Copyright © Голанов А.В., Антипина Н.А., Ветлова Е.Р., Золотова С.В., Галкин М.В., Лестровая А.И., 20232023Голанов А.В., Антипина Н.А., Ветлова Е.Р., Золотова С.В., Галкин М.В., Лестровая А.И.Golanov A.V., Antipina N.A., Vetlova E.R., Zolotova S.V., Galkin M.V., Lestrovaya A.I.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.oncoradjournal.ru/jour/article/view/311

Появление новой техники для стереотаксического облучения на линейных ускорителях, совершенствование систем визуализации и навигации способствовало становлению и быстрому развитию нового направления — экстракраниальной радиохирургии. Сегодня существует возможность прецизионного облучения со стереотаксической точностью различных объемных образований любой локализации, в том числе спинальной. Одним из перспективных и востребованных показаний к применению радиохирургического методаявляются различные первичные и метастатические опухоли и артериовенозные мальформации спинногомозга и позвоночника. Радиохирургическое и гипофракционированное лечение, заключающееся в точном подведении высоких доз ионизирующего излучения к патологической ткани за одну или несколько фракций, позволяет эффективно и безопасно проводить лечение даже радиорезистентных новообразований.В настоящей статье приводятся данные литературы и проанализирован опыт стереотаксического облучения первичных объемных образований спинного мозга и позвоночника в НМИЦ нейрохирургии им.ак. Н.Н. Бурденко. Делается вывод о высокой эффективности (более 90 %) при минимальном количестве осложнений стереотаксического облучения при патологии спинного мозга и позвоночника при длительных сроках наблюдения, что позволяет сохранять качество жизни пациентов.

The emergence of new techniques for stereotaxic irradiation on linear accelerators, the improvement of visualization and navigation systems contributed to the emergence and rapid development of a new direction — extracranial radiosurgery. Today, there is the possibility of precision irradiation with stereotaxic accuracy of various volumetric formations of any, including spinal, localization. One of the promising and popular indications for the using of the radiosurgical method is various primary and metastatic tumors and arteriovenous malformations of the spinal cord and spine. Radiosurgery as well as hypofraction, which consists in accurately delivering of high doses of ionizing radiation to the pathological tissue in one or several fractions, makes it possible to be effective and safe treatment even in cases of radioresistant neoplasms.

This article presents the literature data and analyzes the experience of stereotactic irradiation of primary volumetric formations of the spinal cord and spine in the N.N. Burdenko Neurosurgical Center. It is concluded that stereotactic irradiation is highly effective (> 90 %) with a minimum number of complications in spinal cord and spine pathology with long-term follow-up, which allows maintaining the quality of life of patients.

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The authors declare that there are no conflicts of interest present.