ojrdrtОнкологический журнал: лучевая диагностика, лучевая терапияJournal of oncology: diagnostic radiology and radiotherapy2587-75932713-167XНЕКОММЕРЧЕСКОЕ ПАРТНЕРСТВО «ОБЩЕСТВО ИНТЕРВЕНЦИОННЫХ ОНКОРАДИОЛОГОВ»10.37174/2587-7593-2023-6-2-57-65ojrdrt-299Research ArticleЛУЧЕВАЯ ДИАГНОСТИКАDIAGNOSTIC RADIOLOGYМРТ-диагностика энцефалопатии Вернике: обзор литературы, клинические случаиMRI Diagnostics of Wernicke Encephalopathy: Literature Review, Clinical Caseshttps://orcid.org/0000-0003-0431-2610СашинД. В.SashinD. V.

Сашин Д.В. — к.м.н., врач-рентгенолог, н.с. отделениярентгенодиагностического «НИИ КиЭР», НИМЦ онкологии им. Н.Н. Блохина Минздрава России

115478, Москва, Каширское шоссе, 24

24 Kashirskoye Shosse, Moscow, 115478

denchegs70@gmail.comhttps://orcid.org/0000-0002-3036-2753ГаранинаН. В.GaraninaN. V.

Гаранина Н.В. — врач-рентгенолог НИИ КиЭР НИМЦонкологии им. Н.Н. Блохина Минздрава России

115478, Москва, Каширское шоссе, 24

24 Kashirskoye Shosse, Moscow, 115478

natalia.v@gmail.comhttps://orcid.org/0000-0002-6274-5636МакароваТ. А.MakarovaT. A.

Макарова Т.А. — клинический ординатор второго годакафедры рентгенологии и радиологии, Российская медицинская академия непрерывного профессионального образования Минздрава России.

115478, Москва, Каширское шоссе, 24

24 Kashirskoye Shosse, Moscow, 115478

https://orcid.org/0000-0002-9836-1298ШаленковЕ. А.ShalenkovE. A.

Шаленков Е.А. — ординатор второго года по специальности рентгенология, НИМЦ онкологии им. Н.Н. Блохина Минздрава России

115478, Москва, Каширское шоссе, 24

24 Kashirskoye Shosse, Moscow, 115478

https://orcid.org/0000-0002-3785-7070НечипайЕ. А.NechipayE. A.

Нечипай Э.А. — к.м.н., врач-рентгенолог, н.с. отделениярентгенодиагностического НИИ КиЭР, НИМЦ онкологии им. Н.Н. Блохина Минздрава России

115478, Москва, Каширское шоссе, 24

24 Kashirskoye Shosse, Moscow, 115478

https://orcid.org/0000-0001-6169-2723ЮгайВ. В.YugayV. V.

Югай В.В. — врач-онколог онкологического отделенияхирургических методов лечения №6 (абдоминальной онкологии), НИМЦ онкологии им. Н.Н. Блохина Минздрава России

115478, Москва, Каширское шоссе, 24

24 Kashirskoye Shosse, Moscow, 115478

Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина Минздрава РоссииРоссияN.N. Blokhin National Medical Research Center of OncologyRussian Federation202321062023625765Copyright © Сашин Д.В., Гаранина Н.В., Макарова Т.А., Шаленков Е.А., Нечипай Е.А., Югай В.В., 20232023Сашин Д.В., Гаранина Н.В., Макарова Т.А., Шаленков Е.А., Нечипай Е.А., Югай В.В.Sashin D.V., Garanina N.V., Makarova T.A., Shalenkov E.A., Nechipay E.A., Yugay V.V.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.oncoradjournal.ru/jour/article/view/299

Энцефалопатия Вернике (ЭВ) — это редкое неврологическое расстройство, возникающее вследствие дефицита витамина B1 (тиамина), которое ассоциировано с высокими рисками развития корсаковского психоза и летального исхода при несвоевременном начале специфической терапии. Помимо клинико-лабораторных данных важную роль в выявлении данной патологии играет магнитно-резонансная томография (МРТ) головного мозга, обладающая достаточно высокой специфичностью. Однако для правильной интерпретации данных МРТ необходима высокая степень информированности врачей-рентгенологов об ЭВ.

В настоящей публикации представлено два собственных клинических наблюдения пациентов, которые перенесли оперативные вмешательства на органах желудочно-кишечного тракта, осложнившиеся энцефалопатией Вернике, МРТ-картина и клинические проявления, описаны ключевые особенности этиологии и патогенеза этого патологического процесса.

Wernicke encephalopathy (WE)is a rareneurologicaldisorderinducedby vitaminB1 deficiency(thiamine), which is associated with high risks of Korsakoff psychosis and death in case of untimely initiation ofspecific therapy. In addition to clinical and laboratory data, magnetic resonance imaging (MRI) of the brain, which has a fairly high specificity, plays an important role in detecting this pathology. However, a high degree of awareness ofWE by radiologists is necessary for correct interpretation ofMRI data.

This publication presents two own clinical observations ofpatients who underwent surgical interventions on the gastrointestinal tract, complicated by Wernicke encephalopathy, MRI and clinical manifestations, the key features ofthe etiology and pathogenesis ofthis pathological process are described.

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The authors declare that there are no conflicts of interest present.