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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ojrdrt</journal-id><journal-title-group><journal-title xml:lang="ru">Онкологический журнал: лучевая диагностика, лучевая терапия</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of oncology: diagnostic radiology and radiotherapy</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2587-7593</issn><issn pub-type="epub">2713-167X</issn><publisher><publisher-name>НЕКОММЕРЧЕСКОЕ ПАРТНЕРСТВО «ОБЩЕСТВО ИНТЕРВЕНЦИОННЫХ ОНКОРАДИОЛОГОВ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.37174/2587-7593-2023-6-1-80-87</article-id><article-id custom-type="elpub" pub-id-type="custom">ojrdrt-283</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КЛИНИЧЕСКИЕ СЛУЧАИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASES</subject></subj-group></article-categories><title-group><article-title>Клиническое наблюдение: оценка факторов, связанных с отказом или прекращением лечения у больных раком молочной железы</article-title><trans-title-group xml:lang="en"><trans-title>Clinical Observation: Assessment of Factors Associated with the Refusal or Termination of Treatment in Patients with Breast Cancer</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-2496-8273</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузнецова</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuznetsova</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кузнецова Анна Игоревна — кандидат медицинских наук, доцент, заведующая учебной частью кафедры онкологии, лучевой диагностики и лучевой терапии ЮУГМУ МЗ РФ, старший научный сотрудник.</p><p>454092, Челябинск, ул. Воровского, 64; 634050, Томск, пр. Ленина, 36</p></bio><bio xml:lang="en"><p>64, Vorovsky Str., Chelyabinsk, 454092; 36, Lenin Ave., Tomsk, 634050</p></bio><email xlink:type="simple">ann_rad@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9000-7238</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пахомова</surname><given-names>Я. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Pakhomova</surname><given-names>Ya. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Пахомова Яна Николаевна — кандидат психологических наук, старший научный сотрудник, доцент кафедры психологии, ЧелГУ Минобрнауки России.</p><p>634050, Томск, пр. Ленина, 36; 454001, Челябинск, ул. Братьев Кашириных, 129</p></bio><bio xml:lang="en"><p>36, Lenin Ave., Tomsk, 634050; 129, Kashirin Brothers Str., Chelyabinsk, 454001</p></bio><email xlink:type="simple">sizova159@yandex.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7065-0234</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Циринг</surname><given-names>Д. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Tsiring</surname><given-names>D. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Циринг Диана Александровна — доктор психологических наук, профессор, главный научный сотрудник, директор Уральского филиала Финансового университета при Правительстве Российской Федерации Минобрнауки России.</p><p>634050, Томск, пр. Ленина, 36; 454084, Челябинск, ул. Работниц, 58</p></bio><bio xml:lang="en"><p>36, Lenin Ave., Tomsk, 634050; 58, Rabotnits Str., Chelyabinsk, 454084</p></bio><email xlink:type="simple">L-di@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7912-9039</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Важенин</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Vazhenin</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Важенин Андрей Владимирович — академик РАН, доктор медицинских наук, профессор, заведующий кафедрой онкологии, лучевой диагностики и лучевой терапии ЮУГМУ МЗ РФ.</p><p>454092, Челябинск, ул. Воровского, 64</p></bio><bio xml:lang="en"><p>64, Vorovsky Str., Chelyabinsk, 454092</p></bio><email xlink:type="simple">vav222@mail.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8600-3533</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пономарева</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Ponomareva</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Пономарева Ирина Владимировна — кандидат психологических наук, старший научный сотрудник, заместитель директора Уральского филиала Финансового университета при Правительстве Российской Федерации Минобрнауки России.</p><p>634050, Томск, пр. Ленина, 36; 454084, Челябинск, ул. Работниц, 58; 454001, Челябинск, ул. Братьев Кашириных, 129</p></bio><bio xml:lang="en"><p>36, Lenin Ave., Tomsk, 634050; 58, Rabotnits Str., Chelyabinsk, 454084; 129, Kashirin Brothers Str., Chelyabinsk, 454001</p></bio><email xlink:type="simple">ivp-csu@yandex.ru</email><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3674-754X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Миронченко</surname><given-names>М. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Mironchenko</surname><given-names>M. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Миронченко Марина Николаевна — кандидат медицинских наук, доцент кафедры онкологии, лучевой диагностики и лучевой терапии ЮУГМУ МЗ РФ, заместитель главного врача по медицинской части и научной работе Клиники ЮУГМУ МЗ РФ, старший научный сотрудник.</p><p>454092, Челябинск, ул. Воровского, 64; 634050, Томск, пр. Ленина, 36</p></bio><bio xml:lang="en"><p>64, Vorovsky Str., Chelyabinsk, 454092; 36, Lenin Ave., Tomsk, 634050</p></bio><email xlink:type="simple">thoraxhir@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Демчук</surname><given-names>М. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Demchuk</surname><given-names>M. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Демчук Максим Алексеевич — младший научный сотрудник.</p><p>634050, Томск, пр. Ленина, 36; 454084, Челябинск, ул. Работниц, 58; 454001, Челябинск, ул. Братьев Кашириных, 129</p></bio><bio xml:lang="en"><p>36, Lenin Ave., Tomsk, 634050; 58, Rabotnits Str., Chelyabinsk, 454084; 129, Kashirin Brothers Str., Chelyabinsk, 454001</p></bio><email xlink:type="simple">demchukmax74@gmail.com</email><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2495-1639</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гладков</surname><given-names>Ю. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Gladkov</surname><given-names>Yu. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гладков Юрий Олегович — младший научный сотрудник.</p><p>634050, Томск, пр. Ленина, 36; 454084, Челябинск, ул. Работниц, 58; 454001, Челябинск, ул. Братьев Кашириных, 129</p></bio><bio xml:lang="en"><p>36, Lenin Ave., Tomsk, 634050; 58, Rabotnits Str., Chelyabinsk, 454084; 129, Kashirin Brothers Str., Chelyabinsk, 454001</p></bio><email xlink:type="simple">ug_95@mail.ru</email><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Новикова</surname><given-names>Т. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Novikova</surname><given-names>T. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Новикова Татьяна Сергеевна.</p><p>454092, Челябинск, ул. Воровского, 64</p></bio><bio xml:lang="en"><p>64, Vorovsky Str., Chelyabinsk, 454092</p></bio><email xlink:type="simple">novikovats@chelonco.ru</email><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Южно-Уральский государственный медицинский университет Минздрава России; Национальный исследовательский Томский государственный университет Минобрнауки России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>South Ural State Medical University; National Research Tomsk State University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Национальный исследовательский Томский государственный университет Минобрнауки России; Челябинский государственный университет Минобрнауки России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Research Tomsk State University; Chelyabinsk State University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Национальный исследовательский Томский государственный университет Минобрнауки России; Уральский филиал Финансового университета при Правительстве Российской Федерации Минобрнауки России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Research Tomsk State University; Ural Branch of the Financial University under the Government of the Russian Federation</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Южно-Уральский государственный медицинский университет Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>South Ural State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>Национальный исследовательский Томский государственный университет Минобрнауки России; Уральский филиал Финансового университета при Правительстве Российской Федерации Минобрнауки России; Челябинский государственный университет Минобрнауки России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>National Research Tomsk State University; Ural Branch of the Financial University under the Government of the Russian Federation; Chelyabinsk State University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>30</day><month>03</month><year>2023</year></pub-date><volume>6</volume><issue>1</issue><fpage>80</fpage><lpage>87</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Кузнецова А.И., Пахомова Я.Н., Циринг Д.А., Важенин А.В., Пономарева И.В., Миронченко М.Н., Демчук М.А., Гладков Ю.О., Новикова Т.С., 2023</copyright-statement><copyright-year>2023</copyright-year><copyright-holder xml:lang="ru">Кузнецова А.И., Пахомова Я.Н., Циринг Д.А., Важенин А.В., Пономарева И.В., Миронченко М.Н., Демчук М.А., Гладков Ю.О., Новикова Т.С.</copyright-holder><copyright-holder xml:lang="en">Kuznetsova A.I., Pakhomova Y.N., Tsiring D.A., Vazhenin A.V., Ponomareva I.V., Mironchenko M.N., Demchuk M.A., Gladkov Y.O., Novikova T.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.oncoradjournal.ru/jour/article/view/283">https://www.oncoradjournal.ru/jour/article/view/283</self-uri><abstract><p>Проведен анализ  клинического наблюдения психологических особенностей женщины с диагнозом рак молочной железы,  которая отказалась от части  предложенной терапии, и не имела  противопоказаний  для начала  специального лечения.</p><p>Пациентка Ю.Ф.,  1953 г.р.,  диагноз:   рак  правой   молочной железы  T1NxM0  ЭР(95  %), ПР(15  %), Her2neu(0),  Ki67 (5 %), отказалась по личным причинам от предложенного на первом  этапе  хирургического  лечения, в связи  с чем назначен курс гормонотерапии, курс дистанционной лучевой терапии по радикальной программе. При  оценке  психологического профиля пациентки, полученные данные демонстрируют наличие парадоксальной гиперзащиты. Ее психологический профиль схож с психологическими особенностями женщин, больных раком  молочной железы,  течение болезни которых окончилось  летальным исходом.  В исследовании, проведенном в 2021 г. (проект  №19-18-00426), получены данные  о женщинах с негативным исходом  заболевания (смерть), которые были убеждены в собственной удачливости и в возможности контроля происходящего, использовали широкий спектр стратегий совладания, были  более жизнестойки, оптимистичны и имели  выраженную интернальность по сравнению с женщинами, у которых заболевание перешло  в стойкую ремиссию.</p></abstract><trans-abstract xml:lang="en"><p>The  study  analyzed  the  clinical  observation of the  psychological characteristics  of a woman  diagnosed with  breast cancer,  who refused  part  of the proposed therapy, and had no contraindications to start  special treatment.</p><p>Patient Yu.F., born in 1953, diagnosis: cancer  of the right  breast T1NxM0 ЭР(95 %), ПР(15 %), Her2neu(0), Ki67 (5 %), refused  for personal reasons from the surgical treatment proposed at the 1st stage  (a written refusal was taken), in connection with which  a course  of hormone therapy was prescribed, a course  of remote radiation therapy according to a radical program. When assessing the psychological profile of the patient, the data obtained demonstrate the presence of paradoxical hyperprotection in the patient who refused part of the treatment. Her psychological profile is similar to the psychological characteristics of women with breast cancer, whose course  of the disease ended  in death.  In a study conducted in 2021, data were obtained on women with  a negative outcome of the  disease (death), who were convinced of their  own luck and in the  ability  to control what was happening, used a wide range  of coping  strategies, were more resilient, are optimistic and had a pronounced internality in comparison with women  in whom the disease went into stable  remission.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>рак молочной  железы</kwd><kwd>отказ  от лечения</kwd><kwd>психологический  профиль</kwd><kwd>интернальность</kwd><kwd>стратегии совладания</kwd></kwd-group><kwd-group xml:lang="en"><kwd>breast cancer</kwd><kwd>treatment refusal</kwd><kwd>psychological profile</kwd><kwd>internality</kwd><kwd>coping strategies</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Исследование выполнено за счет гранта Российского научного фонда (проект № 19-18-00426).</funding-statement><funding-statement xml:lang="en">The study had sponsorship by RNF (project № 19-18-00426).</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Клинические рекомендации. 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