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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ojrdrt</journal-id><journal-title-group><journal-title xml:lang="ru">Онкологический журнал: лучевая диагностика, лучевая терапия</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of oncology: diagnostic radiology and radiotherapy</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2587-7593</issn><issn pub-type="epub">2713-167X</issn><publisher><publisher-name>НЕКОММЕРЧЕСКОЕ ПАРТНЕРСТВО «ОБЩЕСТВО ИНТЕРВЕНЦИОННЫХ ОНКОРАДИОЛОГОВ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.37174/2587-7593-2021-4-2-51-59</article-id><article-id custom-type="elpub" pub-id-type="custom">ojrdrt-172</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ИНТЕРВЕНЦИОННАЯ РАДИОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>INTERVENTIONAL RADIOLOGY</subject></subj-group></article-categories><title-group><article-title>Инфекционные осложнения при различных вариантах чрескожного наружно-внутреннего билиарного дренирования при механической желтухе опухолевого генеза</article-title><trans-title-group xml:lang="en"><trans-title>Infectious Complications after Different Percutaneous External-Internal Biliary Drainage Techniques for Malignant Jaundice</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6685-3183</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Охотников</surname><given-names>О. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Okhotnikov</surname><given-names>O. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>хотников Олег Иванович — заведующий отделением рентгенохирургических методов диагностики и лечения №2 Курской областной клинической больницы, профессор кафедры лучевой диагностики и терапии КГМУ, доктор медицинских наук, профессор</p><p>305007, Курск, ул. Карла Маркса, 3; 305007, Курск, ул. Сумская, 45А</p></bio><bio xml:lang="en"><p>3, Karl Marks str., Kursk, Russia 305041; 45-a, Sumskaya str., Kursk, Russia 305007</p></bio><email xlink:type="simple">oleg_okhotnikov@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3452-6652</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Яковлева</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Yakovleva</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Яковлева Марина Валерьевна — доцент кафедры хирургических болезней КГМУ, врач отделения рентгенохирургических методов диагностики и лечения №2 Курской областной клинической больницы, кандидат медицинских наук, доцент</p><p>305007, Курск, ул. Карла Маркса, 3; 305007, Курск, ул. Сумская, 45А</p></bio><bio xml:lang="en"><p>3, Karl Marks str., Kursk, Russia 305041; 45-a, Sumskaya str., Kursk, Russia 305007</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6741-3358</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Григорьев</surname><given-names>С. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Grigoriev</surname><given-names>S. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Григорьев Сергей Николаевич — заведующий отделением гнойной хирургии, врач отделения рентгенохирургических методов диагностики и лечения №2, кандидат медицинских наук</p><p>305007, Курск, ул. Сумская, 45А</p></bio><bio xml:lang="en"><p>45-a, Sumskaya str., Kursk, Russia 305007</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-8421-430X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пахомов</surname><given-names>В. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Pakhomov</surname><given-names>V. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Пахомов Вадим Игоревич — врач отделения рентгенохирургических методов диагностики и лечения №2</p><p>305007, Курск, ул. Сумская, 45А</p></bio><bio xml:lang="en"><p>45-a, Sumskaya str., Kursk, Russia 305007</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4102-1516</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Григорьев</surname><given-names>Н. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Grigoriev</surname><given-names>N. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Григорьев Николай Николаевич — профессор кафедры хирургических болезней, доктор медицинских наук</p><p>305007, Курск, ул. Карла Маркса, 3</p></bio><bio xml:lang="en"><p>3, Karl Marks str., Kursk, Russia 305041</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-3628-2188</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Охотников</surname><given-names>О. О.</given-names></name><name name-style="western" xml:lang="en"><surname>Okhotnikov</surname><given-names>O. O.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Охотников Олег Олегович — студент лечебного факультета </p><p>305007, Курск, ул. Карла Маркса, 3</p></bio><bio xml:lang="en"><p>3, Karl Marks str., Kursk, Russia 305041;</p></bio><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Курский государственный медицинский университет Минздрава России; 	&#13;
Курская областная клиническая больница Комитета здравоохранения Курской области</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kursk State Medical University; &#13;
Kursk Regional Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Курская областная клиническая больница Комитета здравоохранения Курской области</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kursk Regional Clinical Hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Курский государственный медицинский университет Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kursk State Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>22</day><month>06</month><year>2021</year></pub-date><volume>4</volume><issue>2</issue><fpage>51</fpage><lpage>59</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Охотников О.И., Яковлева М.В., Григорьев С.Н., Пахомов В.И., Григорьев Н.Н., Охотников О.О., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Охотников О.И., Яковлева М.В., Григорьев С.Н., Пахомов В.И., Григорьев Н.Н., Охотников О.О.</copyright-holder><copyright-holder xml:lang="en">Okhotnikov O.I., Yakovleva M.V., Grigoriev S.N., Pakhomov V.I., Grigoriev N.N., Okhotnikov O.O.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.oncoradjournal.ru/jour/article/view/172">https://www.oncoradjournal.ru/jour/article/view/172</self-uri><abstract><sec><title>Цель</title><p>Цель: Анализ частоты возникновения инфекционных осложнений при различных вариантах чрескожного наружно-внутреннего билиарного дренирования у пациентов с механической желтухой опухолевого генеза.</p></sec><sec><title>Материал и методы</title><p>Материал и методы: Использовано антеградное наружно-внутреннее дренирование желчного дерева в транспапиллярном и супрапапиллярном вариантах у 110 пациентов. Наружно-внутреннее билиарное дренирование выполнялось этапно, после чрескожной чреспеченочной холангиостомии или вынужденно первично при проксимальной обструкции билиарного дерева с разобщением желчных протоков и невозможности сформировать фиксирующий элемент дренажа проксимальнее зоны обструкции.</p></sec><sec><title>Результаты</title><p>Результаты: В первой группе транспапиллярное наружно-внутреннее дренирование выполнено 30 пациентам с перипапиллярной опухолевой обструкцией. Из 26 пациентов с проксимальной обструкцией супрапапиллярное наружно-внутреннее дренирование проведено 8 пациентам, транспапиллярное — 18 пациентам. Постманипуляционный холангит в первой группе встретился в 16 случаях (28,6 %), абсцессы печени развились 4 случаях (7,1 %). Во второй группе среди 30 пациентов с транспапиллярным дренированием на фоне перипапиллярной опухолевой обструкции признаки острого холангита развились в 4 случаях. Холангит был купирован своевременным переводом наружно-внутреннего дренажа в наружный. Среди 24 пациентов с проксимальной обструкцией желчного дерева супрапапиллярное наружно-внутреннее дренирование без осложнений было выполнено в 18 случаях, транспапиллярное — у 6 больных с проксимальным блоком без разобщения желчного дерева. Острый холангит развился в 2 случаях. У пациентов второй группы холангигенных абсцессов печени не было. Случаев госпитальной летальности в обеих группах не было.</p></sec><sec><title>Заключение</title><p>Заключение: Причиной развития постманипуляционного холангита и абсцессов печени при наружно-внутреннем дренировании желчного дерева на фоне его опухолевой обструкции является транспапиллярное положение эндобилиарного дренажа с дуодено-билиарным рефлюксом на фоне персистирующей билиарной гипертензии. Для супрапапиллярного расположения дренажа при чрескожном дренировании проксимальной опухолевой обструкции желчного дерева с разобщением протоков риск постманипуляционного холангита в недренируемых сегментах печени минимален.</p><p>При возникновении постманипуляционного холангита в случае транспапиллярного дренирования Охотников желчного дерева необходима временная трансформация наружно-внутреннего дренажа в наружную холангиостому.</p></sec></abstract><trans-abstract xml:lang="en"><sec><title>Purpose</title><p>Purpose: Analysis of infectious complications incidence in different types of percutaneous externalinternal biliary drainage in patients with obstructive jaundice of tumor genesis.</p></sec><sec><title>Material and methods</title><p>Material and methods: The results of using antegrade external-internal drainage of the biliary tree in transpapillary and suprapapillary variants in 110 patients were analyzed. External-internal biliary drainage was performed in stages, after percutaneous transhepatic cholangiostomy or involuntarily primary with proximal obstruction of the biliary tree with bile duct segregation if it is impossible to form a fixing element of drainage proximal to the obstruction zone.</p></sec><sec><title>Results</title><p>Results: In the first group, transpapillary external-internal drainage was performed in 30 patients with peripapillary tumor obstruction. Of the 26 patients with proximal obstruction, suprapapillary external-internal drainage was performed in 8 patients, transpapillary — in 18 patients. Postmanipulation cholangitis in the first group occurred in 16 cases (28.6 %), liver abscesses developed 4 cases (7.1 %). In the second group, among 30 patients with transpapillary drainage on the background of peripapillary tumor obstruction, signs of acute cholangitis developed in 4 cases. Cholangitis was stopped by timely transfer of external-internal drainage to external. Among 24 patients with proximal obstruction of the biliary tree, suprapapillary external-internal drainage without complications was performed in 18 cases, transpapillary in 6 patients with the proximal block without disconnecting of the biliary tree. Acute cholangitis developed in 2 cases. Patients of the second group had no liver cholangigenic abscesses. There were no cases of hospital mortality in both groups.</p></sec><sec><title>Conclusion</title><p>Conclusion: Factors in the development of postmanipulation cholangitis and liver abscesses during external-internal drainage of the biliary tree against the background of its tumor obstruction are the transpapillary position of endobiliary drainage with duodeno-biliary reflux in persistent biliary hypertension. In the case of suprapapillary location of the working end of external-internal drainage during antegrade drainage of the proximal tumor obstruction of the biliary tree with dissociation, the risk of postmanipulation cholangitis in non-drained liver segments is minimal. In the event of post-manipulation cholangitis in the case of transpapillary drainage of the biliary tree, a temporary transformation of external-internal drainage into external cholangiostomy is necessary.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>желчные протоки</kwd><kwd>опухолевая обструкция</kwd><kwd>механическая желтуха</kwd><kwd>супрапапиллярное дренирование</kwd><kwd>транспапиллярное дренирование</kwd><kwd>холангит</kwd></kwd-group><kwd-group xml:lang="en"><kwd>bile ducts</kwd><kwd>obstructive jaundice</kwd><kwd>tumor obstruction of the bile ducts</kwd><kwd>suprapapillary drainage</kwd><kwd>transpapillary drainage</kwd><kwd>cholangitis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Misra SP, Dwivedi M. Reflux of duodenal contents and cholangitis in patients undergoing self-expanding metal stent placement. Gastrointest Endosc 2009;70 (2):317-21. 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