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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ojrdrt</journal-id><journal-title-group><journal-title xml:lang="ru">Онкологический журнал: лучевая диагностика, лучевая терапия</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of oncology: diagnostic radiology and radiotherapy</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2587-7593</issn><issn pub-type="epub">2713-167X</issn><publisher><publisher-name>НЕКОММЕРЧЕСКОЕ ПАРТНЕРСТВО «ОБЩЕСТВО ИНТЕРВЕНЦИОННЫХ ОНКОРАДИОЛОГОВ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.37174/2587-7593-2021-4-1-53-64</article-id><article-id custom-type="elpub" pub-id-type="custom">ojrdrt-157</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КОМБИНИРОВАННЫЕ МЕТОДЫ ДИАГНОСТИКИ И ЛЕЧЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>COMBINED METHODS OF DIAGNOSTICS AND TREATMENT</subject></subj-group></article-categories><title-group><article-title>Обзор классификаций промежуточной стадии гепатоцеллюлярной карциномы</article-title><trans-title-group xml:lang="en"><trans-title>Intermediate Stage Hepatocellular Carcinoma Classifications: the Review</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3429-3708</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хайцман</surname><given-names>Д. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Khaitsman</surname><given-names>D. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант, врач отделения рентгенохирургических методов диагностики и лечения,</p><p>115478, Москва, Каширское шоссе, 24</p></bio><bio xml:lang="en"><p>24 Kashirskoye Highway, Moscow 115478</p></bio><email xlink:type="simple">d.khaitsman@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4587-4153</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Погребняков</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Pogrebnyakov</surname><given-names>I. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, и.о. заведующего отделением рентгенохирургических методов диагностики и лечения,</p><p>115478, Москва, Каширское шоссе, 24</p></bio><bio xml:lang="en"><p>24 Kashirskoye Highway, Moscow 115478</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-4006-3642</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Виршке</surname><given-names>Э. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Virshke</surname><given-names>E. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, заведующий рентгенооперационным блоком отдела интервенционной радиологии,</p><p>115478, Москва, Каширское шоссе, 24</p></bio><bio xml:lang="en"><p>24 Kashirskoye Highway, Moscow 115478</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-5800-8684</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Трофимов</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Trofimov</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач по рентгенэндоваскулярным диагностике и лечению отделения рентгенохирургических методов диагностики и лечения,</p><p>115478, Москва, Каширское шоссе, 24</p></bio><bio xml:lang="en"><p>24 Kashirskoye Highway, Moscow 115478</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6331-5611</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Францев</surname><given-names>Д. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Frantsev</surname><given-names>D. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>кандидат медицинских наук, врач по рентгенэндоваскулярным диагностике и лечению отделения рентгенохирургических методов диагностики и лечения,</p><p>115478, Москва, Каширское шоссе, 24</p></bio><bio xml:lang="en"><p>24 Kashirskoye Highway, Moscow 115478</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6323-511X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Джанян</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Dzhanyan</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>врач отделения химиотерапии №17,</p><p>115478, Москва, Каширское шоссе, 24</p></bio><bio xml:lang="en"><p>24 Kashirskoye Highway, Moscow 115478</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6244-4294</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бредер</surname><given-names>В. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Breder</surname><given-names>V. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор медицинских наук, ведущий научный сотрудник отделения химиотерапии №17,</p><p>115478, Москва, Каширское шоссе, 24</p></bio><bio xml:lang="en"><p>24 Kashirskoye Highway, Moscow 115478</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-7185-7165</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Долгушин</surname><given-names>Б. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Dolgushin</surname><given-names>B. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>академик РАН, доктор медицинских наук, профессор, заместитель директора по научной и лечебной работе  — директор НИИ КиЭР,</p><p>115478, Москва, Каширское шоссе, 24</p></bio><bio xml:lang="en"><p>24 Kashirskoye Highway, Moscow 115478</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Национальный медицинский исследовательский центр онкологии им. Н.Н. Блохина Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>N.N. Blokhin National Medical Research Center of Oncology</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>12</day><month>04</month><year>2021</year></pub-date><volume>4</volume><issue>1</issue><fpage>53</fpage><lpage>64</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Хайцман Д.М., Погребняков И.В., Виршке Э.Р., Трофимов И.А., Францев Д.Ю., Джанян И.А., Бредер В.В., Долгушин Б.И., 2021</copyright-statement><copyright-year>2021</copyright-year><copyright-holder xml:lang="ru">Хайцман Д.М., Погребняков И.В., Виршке Э.Р., Трофимов И.А., Францев Д.Ю., Джанян И.А., Бредер В.В., Долгушин Б.И.</copyright-holder><copyright-holder xml:lang="en">Khaitsman D.M., Pogrebnyakov I.V., Virshke E.R., Trofimov I.A., Frantsev D.Y., Dzhanyan I.A., Breder V.V., Dolgushin B.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.oncoradjournal.ru/jour/article/view/157">https://www.oncoradjournal.ru/jour/article/view/157</self-uri><abstract><p>Заболеваемость гепатоцеллюлярной карценомой (ГЦК) остается пока высокой — данная нозология занимает пятое место в мире среди онкологических заболеваний. Подходы к лечению варьируются в зависимости от распространенности опухолевого процесса. Согласно классификации BCLC, пациентам со стадией В рекомендовано проведение трансартериальной химиоэмболизации (ТАХЭ), однако в эту группу входят пациенты с различной степенью внутрипеченочного распространения опухоли, а также с различным функциональным состоянием печени. Разрабатываются новые классификации, которые определяют тактику лечения и прогноз выживаемости, принимая во внимание гетерогенность данной группы больных. Целью настоящей работы является литературный обзор существующих классификаций и описание их прогностического значения. </p></abstract><trans-abstract xml:lang="en"><p>Hepatocellular carcinoma is the fifth most common cancer worldwide and the approaches to treatmentdiffer due to the stage of the disease. According to BCLC classification, B stage patients are recommendedto be underwent transarterial chemoembolization. However, BCLC B integrates patients with differentintrahepatic tumor burden and with different liver deterioration. There are many staging classifications thatdetermine the treatment and survival rates due to heterogeneity of this patient cohort. The aim of this studyis to review the existing ones and to describe their prognostic value.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>гепатоцеллюлярная карцинома</kwd><kwd>трансартериальная химиоэмболизация</kwd><kwd>классификация BCLC</kwd></kwd-group><kwd-group xml:lang="en"><kwd>hepatocellular carcinoma</kwd><kwd>transarterial chemoembolization</kwd><kwd>BCLC classification</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Fitzmaurice C, Akinyemiju T, Abera S, Ahmed M, Alam N, Alemayohu MA, et al. 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