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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ojrdrt</journal-id><journal-title-group><journal-title xml:lang="ru">Онкологический журнал: лучевая диагностика, лучевая терапия</journal-title><trans-title-group xml:lang="en"><trans-title>Journal of oncology: diagnostic radiology and radiotherapy</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2587-7593</issn><issn pub-type="epub">2713-167X</issn><publisher><publisher-name>НЕКОММЕРЧЕСКОЕ ПАРТНЕРСТВО «ОБЩЕСТВО ИНТЕРВЕНЦИОННЫХ ОНКОРАДИОЛОГОВ»</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.37174/2587-7593-2020-3-2-43-50</article-id><article-id custom-type="elpub" pub-id-type="custom">ojrdrt-119</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>КОМБИНИРОВАННЫЕ МЕТОДЫ ДИАГНОСТИКИ И ЛЕЧЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>COMBINED METHODS OF DIAGNOSTICS AND TREATMENT</subject></subj-group></article-categories><title-group><article-title>Локальная гипертермия в неоадъювантной химиолучевой терапии рака прямой кишки</article-title><trans-title-group xml:lang="en"><trans-title>Regional Hyperthermia in Neo-Adjuvant Chemoradiotherapy of Rectal Cancer</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8740-9471</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Игнатенков</surname><given-names>С. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Ignatenkov</surname><given-names>S. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Игнатенков Станислав Юрьевич — врач-радиотерапевт.</p><p>248007 Калуга, ул. Вишневского, 2</p></bio><bio xml:lang="en"><p>Vishnevsky Str., Kaluga, 248007</p></bio><email xlink:type="simple">snagl1990@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3811-3612</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кудрявцев</surname><given-names>И. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Kudryavtsev</surname><given-names>I. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кудрявцев Игорь Юрьевич — доктор медицинских наук, проф. ФГБОУ КГУ им. К.Э. Циолковского, зам. главного врача по медицинской части, ГБУЗ КО «Калужский областной клинический онкологический диспансер». SPIN-код: 6551-0300, AuthorID: 923800.</p><p>248007 Калуга, ул. Вишневского, 2; 248023 Калуга, ул. Степана Разина, 26</p></bio><bio xml:lang="en"><p>Vishnevsky Str., Kaluga, 248007; 26 Stepan Razin Str., Kaluga, 248023</p></bio><email xlink:type="simple">i-kudryavcev@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2832-742X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кузьминых</surname><given-names>К. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kuzminykh</surname><given-names>K. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кузьминых Константин Александрович — врач-радиолог.</p><p>248007 Калуга, ул. Вишневского, 2</p></bio><bio xml:lang="en"><p>Vishnevsky Str., Kaluga, 248007</p></bio><email xlink:type="simple">kuzminyx.1984@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8270-4359</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Скугарева</surname><given-names>О. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Skugareva</surname><given-names>O. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Скугарева Ольга Александровна — кандидат медицинских наук, зав. радиотерапевтическим отделением.</p><p>248007 Калуга, ул. Вишневского, 2</p></bio><bio xml:lang="en"><p>Vishnevsky Str., Kaluga, 248007</p></bio><email xlink:type="simple">oskugareva@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-1237-8329</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Добросоцкая</surname><given-names>Э. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Dobrosotskaya</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Добросоцкая Элина Алексеевна — студент.</p><p>248023 Калуга, ул. Степана Разина, 26</p></bio><bio xml:lang="en"><p>26 Stepan Razin Str., Kaluga, 248023</p></bio><email xlink:type="simple">dobrosotskaya@list.ru</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБУЗ КО Калужский областной клинический онкологический диспансер</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kaluga Regional Clinical Oncology Center</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ГБУЗ КО Калужский областной клинический онкологический диспансер; ФГБОУ ВО «Калужский государственный университет им. К.Э. Циолковского</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Kaluga Regional Clinical Oncology Center; K.E. Tsiolkovsky Kaluga State University;</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>ФГБОУ ВО Калужский государственный университет им. К.Э. Циолковского</institution><country>Россия</country></aff><aff xml:lang="en"><institution>K.E. Tsiolkovsky Kaluga State University;</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2020</year></pub-date><pub-date pub-type="epub"><day>19</day><month>06</month><year>2020</year></pub-date><volume>3</volume><issue>2</issue><fpage>43</fpage><lpage>50</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Игнатенков С.Ю., Кудрявцев И.Ю., Кузьминых К.А., Скугарева О.А., Добросоцкая Э.А., 2020</copyright-statement><copyright-year>2020</copyright-year><copyright-holder xml:lang="ru">Игнатенков С.Ю., Кудрявцев И.Ю., Кузьминых К.А., Скугарева О.А., Добросоцкая Э.А.</copyright-holder><copyright-holder xml:lang="en">Ignatenkov S.Y., Kudryavtsev I.Y., Kuzminykh K.A., Skugareva O.A., Dobrosotskaya E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.oncoradjournal.ru/jour/article/view/119">https://www.oncoradjournal.ru/jour/article/view/119</self-uri><abstract><p>Рак прямой кишки является одним из самых распространенных злокачественных образований органов желудочно-кишечного тракта. Результаты исследований последних лет показали высокую эффективность и влияние неоадъювантной химиолучевой терапии на число сфинктеросохраняющих хирургических вмешательств, локорегионарный контроль. В статье рассматривается эффективность и безопасность предоперационной химиолучевой терапии на фоне локальной гипертермии при лечении местнораспространенного рака прямой кишки.</p></abstract><trans-abstract xml:lang="en"><p>Rectal cancer is one of the most common malignant tumors of the gastrointestinal tract. Recent studies have shown the high efficiency and impact of neoadjuvant chemoradiotherapy on the number of sphincterpreserving surgeries, and local-regional control. The article discusses the effectiveness and safety of preoperative chemoradiotherapy against the background of regional hyperthermia in the treatment of locally advanced rectal cancer.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>рак прямой кишки</kwd><kwd>комбинированное лечение</kwd><kwd>предоперационная химиолуневая терапия</kwd><kwd>локальная гипертермия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>rectal cancer</kwd><kwd>combined treatment</kwd><kwd>preoperative chemoradiotherapy</kwd><kwd>regional hyperthermia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Каприн АД, Старинский ВВ, Петрова ГВ. Состояние онкологической помощи населению России в 2018 году. М. 2019. 236 c.</mixed-citation><mixed-citation xml:lang="en">Kaprin AD, Starinskii VV, Petrova GV. The Status of Cancer Care for the Population of Russia in 2018. Moscow. 2019. 236. 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